{"id":"W7035748048","doi":"","title":"Analyzing the genetic landscape of French-Canadian hereditary breast cancer women that carry pathogenic BRCA1 or BRCA2 variants","year":2021,"lang":"en","type":"dissertation","venue":"Open MIND","topic":"Health, Education, and Aging","field":"Social Sciences","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Breast cancer; Hereditary Cancer; Cancer; Carry (investment); Mutation; Disease; Germline; Genetic variants","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005241887,0.0003285116,0.0002418889,0.001135606,0.002538585,0.0008960249,0.0006015056,0.0004318645,0.005047937],"category_scores_gemma":[0.001905112,0.000150062,0.0003558733,0.002001839,0.0004219476,0.0001627572,0.0004733374,0.000468888,0.0004416205],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.008951658,"about_ca_system_score_gemma":0.008276019,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_topic_score_codex":0.9527457,"about_ca_topic_score_gemma":0.9718248,"domain_scores_codex":[0.9996232,0.00004694079,0.00000807907,0.00006698344,0.00008877165,0.0001660126],"domain_scores_gemma":[0.9990836,0.0001311517,0.00008288627,0.00002103348,0.0004091822,0.0002719979],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0002636495,0.00008293772,0.9404892,0.00004365792,0.00008472441,0.0006543151,0.00471294,0.0003527357,0.002575716,0.0006669696,0.01826567,0.03180748],"study_design_scores_gemma":[0.000009235594,0.0000347857,0.9835185,0.00004200837,0.00003627317,0.0002944889,0.006736914,0.0002613241,0.0002597461,0.0001391299,0.008652344,0.00001527579],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9864262,0.001076718,0.0002801704,0.003187569,0.00006361057,0.00003414366,0.002437818,0.00001569097,0.006478151],"genre_scores_gemma":[0.9892052,0.001346277,0.0006788279,0.0007951496,0.00003348425,0.0000232246,0.001177493,0.00002394395,0.006716274],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04725426,"threshold_uncertainty_score":0.09506506,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03127582961255228,"score_gpt":0.3354174751263752,"score_spread":0.3041416455138229,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}