{"id":"W7035748048","doi":"","title":"Analyzing the genetic landscape of French-Canadian hereditary breast cancer women that carry pathogenic BRCA1 or BRCA2 variants","year":2021,"lang":"en","type":"dissertation","venue":"Open MIND","topic":"Health, Education, and Aging","field":"Social Sciences","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Breast cancer; Hereditary Cancer; Cancer; Carry (investment); Mutation; Disease; Germline; Genetic variants","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001018749,0.000182602,0.0003535946,0.0001314113,0.0008803256,0.0002924852,0.0008342544,0.0002492394,0.02503759],"category_scores_gemma":[0.00005974262,0.0001439665,0.00006182006,0.0005850861,0.00006112231,0.0002047595,0.00002041364,0.0002636008,0.00003615611],"about_ca_system_candidate":true,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003600387,"about_ca_system_score_gemma":0.02116842,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_topic_score_codex":0.7033296,"about_ca_topic_score_gemma":0.9818531,"domain_scores_codex":[0.997983,0.0003767805,0.0003318704,0.0004267672,0.0003214378,0.0005601539],"domain_scores_gemma":[0.998683,0.0001320392,0.0002755355,0.0003308105,0.0002124125,0.0003662492],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"qualitative","study_design_gemma":"observational","study_design_scores_codex":[0.00003188129,0.00007438686,0.04732387,0.0001495677,0.0002829721,0.00007359905,0.4927238,0.00001698502,0.00005679272,0.00001339287,0.004629971,0.4546228],"study_design_scores_gemma":[0.0002599877,0.00001911299,0.6100187,0.0005489024,0.0001564282,0.00001034643,0.3184138,0.00001837899,0.00002648073,0.00006175329,0.07005211,0.0004139712],"study_design_candidate":"qualitative","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9568576,0.003125244,7.428106e-7,0.001265815,0.00181664,0.0005538362,0.0004630135,0.000001625637,0.03591554],"genre_scores_gemma":[0.9454209,0.002478586,0.0002180195,0.0001031541,0.001215115,0.00007851682,0.0004782311,0.00003372038,0.04997379],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5626948,"threshold_uncertainty_score":0.9843807,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03127582961255228,"score_gpt":0.3354174751263752,"score_spread":0.3041416455138229,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}