{"id":"W7036551815","doi":"","title":"Characterization of Psilocin and Psilocybin Pharmacodynamics in Mouse Models for the Development of Novel Anti-Depressants","year":2024,"lang":"en","type":"dissertation","venue":"University Library (University of Saskatchewan)","topic":"Insect-Plant Interactions and Control","field":"Agricultural and Biological Sciences","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Psilocybin; Hallucinogen; Lysergic acid diethylamide; Open field; Behavioural despair test; In vivo; Pharmacodynamics; Psychopharmacology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008790738,0.0013223,0.0009356911,0.002707183,0.0004703832,0.0008592064,0.0007738703,0.001304916,0.004980802],"category_scores_gemma":[0.000261761,0.000605102,0.001072917,0.0007695441,0.0008764267,0.001039266,0.0003312414,0.004359541,0.001891663],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000704587,"about_ca_system_score_gemma":0.0005922178,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001110424,"about_ca_topic_score_gemma":0.002600569,"domain_scores_codex":[0.9992558,0.00006385448,0.00006629426,0.000190113,0.0002597533,0.0001640265],"domain_scores_gemma":[0.9993611,0.00005808134,0.0001845844,0.00006470975,0.00008919816,0.0002423957],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000818473,0.0007714884,0.000433328,0.0001200724,0.00003172121,0.0001205074,0.00006425686,0.0001781282,0.9937827,0.000310026,0.0002867095,0.003082657],"study_design_scores_gemma":[0.0003504496,0.01318727,0.01638349,0.0001067613,0.0002366503,0.0007604979,0.0002334538,0.002992768,0.9537222,0.0004312016,0.0115425,0.00005278569],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9260419,0.009361632,0.03916191,0.001412851,0.0006464563,0.001517142,0.01305466,0.001192109,0.007611363],"genre_scores_gemma":[0.9000151,0.01495846,0.02937016,0.0010245,0.0002307719,0.004569875,0.01024627,0.0005063383,0.03907849],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004980802,"threshold_uncertainty_score":0.01666242,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01216232477785485,"score_gpt":0.1837846189469811,"score_spread":0.1716222941691262,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}