{"id":"W7036816043","doi":"","title":"Co-administration of pramlintide and insulin via an automated dual-hormone artificial pancreas system to regulate glucose levels in adults living with type 1 diabetes: a randomized, controlled, crossover trial","year":2025,"lang":"en","type":"dissertation","venue":"eScholarship@McGill (McGill)","topic":"Biological Control of Invasive Species","field":"Agricultural and Biological Sciences","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Canadian Institutes of Health Research","keywords":"Artificial pancreas; Insulin; Crossover study; Pancreas; Glucose clamp technique; Crossover","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.002713466,0.0007543488,0.002859239,0.0001649955,0.0004846139,0.0002003474,0.0003884248,0.0009553967,0.00005732699],"category_scores_gemma":[0.005205914,0.0003421119,0.0003592344,0.0008131926,0.000155321,0.0004384356,0.00006676754,0.0006678509,0.00001458566],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002322517,"about_ca_system_score_gemma":0.0000647062,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006409186,"about_ca_topic_score_gemma":0.01106853,"domain_scores_codex":[0.994029,0.001585542,0.001988654,0.001127343,0.0006426401,0.0006268478],"domain_scores_gemma":[0.9947323,0.002597523,0.001319459,0.0002253823,0.0008372492,0.0002880963],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.7098984,0.0004039287,0.0000222554,0.0002040277,0.000309855,0.0000304131,0.00001648587,0.00001573042,0.2545197,0.003643993,0.000001153698,0.03093413],"study_design_scores_gemma":[0.7441476,0.01891601,0.1037004,0.009915285,0.00152778,0.00003367241,0.002495589,0.002001648,0.109277,0.00345685,0.0004961067,0.004032],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9910811,0.0005631487,7.49466e-8,0.000039177,0.0003558002,0.005048054,0.0008714627,0.0003008813,0.001740264],"genre_scores_gemma":[0.9980258,0.0001036302,0.0001227852,0.0000998259,0.0001114227,0.0005132746,0.0007337793,0.00001191277,0.0002776099],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1452427,"threshold_uncertainty_score":0.9999031,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01601012676589766,"score_gpt":0.2451375658225524,"score_spread":0.2291274390566547,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}