{"id":"W7038729174","doi":"","title":"Investigating the impact of POLA2 expression on cytarabine efficacy in acute myeloid leukemia","year":2025,"lang":"en","type":"dissertation","venue":"eScholarship@McGill (McGill)","topic":"Nephrotoxicity and Medicinal Plants","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Myeloid leukemia; Cytarabine; Leukemia; Disease; Myeloid; Expression (computer science)","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.001133519,0.0008547244,0.001461862,0.0008729761,0.0004722702,0.00002619454,0.0005985264,0.0009302034,0.0001161673],"category_scores_gemma":[0.002745961,0.0005921955,0.0006086226,0.001122102,0.00009766052,0.0002638765,0.0001121055,0.003437972,0.00005534563],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001580814,"about_ca_system_score_gemma":0.0005924582,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00164006,"about_ca_topic_score_gemma":0.0004132597,"domain_scores_codex":[0.9955354,0.0004138499,0.001279603,0.0009073041,0.001110483,0.0007533642],"domain_scores_gemma":[0.9967166,0.0007802497,0.0008118596,0.0009949364,0.0002773896,0.000418926],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00253415,0.0005655698,0.0003076439,0.0008870368,0.0005546908,0.0002210032,0.00006776876,0.0001670765,0.9404035,0.001366442,0.00006992445,0.05285517],"study_design_scores_gemma":[0.006372895,0.001763011,0.07229608,0.01887245,0.0008007466,0.00009319986,0.0005688204,0.00007150116,0.8948478,0.00199942,0.001492417,0.000821746],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9643954,0.0002236569,4.106635e-8,0.00004967185,0.0004733976,0.001851496,0.0007239721,0.0001011004,0.03218129],"genre_scores_gemma":[0.9916874,0.0003433026,0.0001872722,0.0005744592,0.00008317098,0.0001144445,0.001484486,0.0001079253,0.005417508],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07198843,"threshold_uncertainty_score":0.9996529,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02217711660144671,"score_gpt":0.3008966911088675,"score_spread":0.2787195745074207,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}