{"id":"W7043187070","doi":"","title":"In search of selective inhibitors of cysteine protease, cathepsin K","year":2005,"lang":"en","type":"article","venue":"NPARC","topic":"Protease and Inhibitor Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Cysteine; Enzyme; Cathepsin O; Enzyme inhibitor; Cathepsin H","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006907475,0.0003182161,0.000564563,0.00036358,0.0004419174,0.0007699347,0.0005191544,0.0009190159,0.01152361],"category_scores_gemma":[0.0006598394,0.0001463478,0.0002411077,0.0002572852,0.000298823,0.000658133,0.0004494896,0.0008606595,0.004513509],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003265525,"about_ca_system_score_gemma":0.0008227391,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002712963,"about_ca_topic_score_gemma":0.0006959839,"domain_scores_codex":[0.9997247,0.00003764124,0.00001662579,0.00005666361,0.000120487,0.0000437809],"domain_scores_gemma":[0.9995711,0.00007837503,0.00006156534,0.00003024634,0.000153144,0.0001055308],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001459731,0.0003539716,0.002901029,0.002652942,0.0001068299,0.001516957,0.0001641625,0.0003679666,0.5977922,0.01076565,0.04707971,0.3348388],"study_design_scores_gemma":[0.0003213466,0.001535451,0.003654995,0.0001278887,0.0001922055,0.00329426,0.0001910084,0.001224369,0.4329579,0.002056143,0.5544105,0.00003385306],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.4333703,0.2945554,0.03668096,0.03804488,0.01881221,0.001023237,0.001350446,0.001072331,0.1750903],"genre_scores_gemma":[0.5796452,0.1117468,0.02356174,0.005857573,0.003789338,0.0003004082,0.00196598,0.000133807,0.2729991],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01152361,"threshold_uncertainty_score":0.03855032,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008039695825627096,"score_gpt":0.246219980626882,"score_spread":0.2381802848012549,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}