{"id":"W7043202727","doi":"","title":"Role of DNA methylation in skeletal metastasis and bone remodeling: diagnostic, prognostic and therapeutic implications","year":2016,"lang":"en","type":"dissertation","venue":"eScholarship@McGill (McGill)","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"DNA methylation; Metastasis; DNA; Bone metastasis; Methylation; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008428648,0.0002100781,0.0002468562,0.0006040765,0.0003497517,0.0009139578,0.000335433,0.0005130097,0.004849895],"category_scores_gemma":[0.001331754,0.0001878481,0.0001604338,0.0004675379,0.0008381387,0.000362866,0.0004021136,0.000805715,0.0007954358],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006949767,"about_ca_system_score_gemma":0.0008590905,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005086401,"about_ca_topic_score_gemma":0.009997884,"domain_scores_codex":[0.9997706,0.0000614998,0.000009032013,0.00004034017,0.00007239851,0.00004617338],"domain_scores_gemma":[0.9996572,0.0001476839,0.00005600096,0.00001930129,0.00005711555,0.0000627315],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001394871,0.0001830648,0.1126779,0.000540696,0.0001336126,0.001390683,0.0009769208,0.0007321601,0.1138312,0.01760481,0.02174782,0.7287861],"study_design_scores_gemma":[0.0001523346,0.0009148096,0.5909355,0.0005208801,0.0002609501,0.00728282,0.00131834,0.001594303,0.0683881,0.02508272,0.3033801,0.0001691281],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"methods","genre_scores_codex":[0.3387613,0.5079746,0.005253193,0.07232486,0.001251416,0.0000810208,0.001782818,0.0001385506,0.07243224],"genre_scores_gemma":[0.8502008,0.09876454,0.002703444,0.003123211,0.0009678777,0.000051599,0.0003624177,0.00004178774,0.04378434],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.005086401,"threshold_uncertainty_score":0.01622444,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01365020880900563,"score_gpt":0.2595908807338438,"score_spread":0.2459406719248382,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}