{"id":"W7047749903","doi":"","title":"Identification of the regulators of the immune checkpoint B7-H4 in a triple-negative breast cancer cell line","year":2019,"lang":"en","type":"dissertation","venue":"eScholarship@McGill (McGill)","topic":"Superconducting Materials and Applications","field":"Engineering","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Fonds de Recherche du Québec - Santé; McGill University Health Centre","keywords":"CRISPR; Identification (biology); Immune system; Gene; Breast cancer; Immune checkpoint; Cancer","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002291472,0.0001400931,0.0002095919,0.0002935085,0.0003877448,0.0006240297,0.0003075439,0.0003549899,0.003540192],"category_scores_gemma":[0.0001707839,0.0001699604,0.0002677372,0.0002458116,0.0002031223,0.0001634926,0.0003105397,0.0008019464,0.002034034],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005181968,"about_ca_system_score_gemma":0.0005437863,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002030877,"about_ca_topic_score_gemma":0.003809467,"domain_scores_codex":[0.9998203,0.00001360712,0.00001234516,0.00003706457,0.00008899321,0.0000275808],"domain_scores_gemma":[0.9998947,0.00001935927,0.00001407043,0.0000198353,0.00002783869,0.00002415761],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004395213,0.00002095524,0.0003834813,0.00002960438,0.00000496878,0.00007470429,0.00005219505,0.00006994127,0.9949994,0.0004407289,0.0005939013,0.003286161],"study_design_scores_gemma":[0.00002477396,0.0002299563,0.007665038,0.00002305913,0.00002792966,0.0003478975,0.0001851564,0.0009344922,0.9649588,0.0002195795,0.02537055,0.00001270508],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9521618,0.002746538,0.01324491,0.001259944,0.0002128702,0.0001798333,0.004479817,0.0003368515,0.02537751],"genre_scores_gemma":[0.9159964,0.002481406,0.01181803,0.000517985,0.00002281374,0.0002316616,0.00738904,0.0001659459,0.06137669],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003540192,"threshold_uncertainty_score":0.01184309,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01033604170141571,"score_gpt":0.2251057469825092,"score_spread":0.2147697052810935,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}