{"id":"W7047749903","doi":"","title":"Identification of the regulators of the immune checkpoint B7-H4 in a triple-negative breast cancer cell line","year":2019,"lang":"en","type":"dissertation","venue":"eScholarship@McGill (McGill)","topic":"Superconducting Materials and Applications","field":"Engineering","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Fonds de Recherche du Québec - Santé; McGill University Health Centre","keywords":"CRISPR; Identification (biology); Immune system; Gene; Breast cancer; Immune checkpoint; Cancer","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000578639,0.0003893315,0.0005655479,0.0001171902,0.0002049337,0.00002535031,0.0007795127,0.0003900164,0.0001553247],"category_scores_gemma":[0.000143625,0.0002927624,0.0003268369,0.0006981571,0.00006438251,0.0002864992,0.00008456202,0.0006066489,0.00001503424],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004241568,"about_ca_system_score_gemma":0.00004883541,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002245768,"about_ca_topic_score_gemma":0.001928813,"domain_scores_codex":[0.9974794,0.0001663292,0.001274765,0.0004053162,0.0003977114,0.0002764355],"domain_scores_gemma":[0.9978362,0.00009643505,0.0007113441,0.001028731,0.0002832887,0.00004405862],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003112835,0.000080191,0.00006256751,0.0005991862,0.00006914261,1.281475e-7,0.00006912089,0.001467255,0.9923622,0.002255945,0.000001016831,0.00300209],"study_design_scores_gemma":[0.0004853211,0.00000884803,0.02336482,0.0005571289,0.0001077388,0.000002508821,0.000702782,0.0001770901,0.9728711,0.001246472,0.0001828953,0.0002932765],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9920905,0.0003723703,1.229507e-7,0.00001966477,0.002008724,0.001087566,0.001979402,0.00005858098,0.002383061],"genre_scores_gemma":[0.9975482,0.0002505148,0.00002919856,0.000007717346,0.0000300018,0.000238614,0.00009301002,0.0001167203,0.001686015],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02330225,"threshold_uncertainty_score":0.9999524,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01033604170141571,"score_gpt":0.2251057469825092,"score_spread":0.2147697052810935,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}