{"id":"W7051522516","doi":"","title":"O antigen biosynthesis in Gram-negative bacteria: Characterization of alpha1,4-glucosyltransferase WclY from Escherichia coli O117 and development of glycosyltransferase inhibitors.","year":2019,"lang":"en","type":"dissertation","venue":"QSpace (Queen's University Library)","topic":"Particle Detector Development and Performance","field":"Physics and Astronomy","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"Canadian Glycomics Network","keywords":"Glycosyltransferase; Escherichia coli; Bacteria; Biosynthesis; Enzyme; Virulence; Antigen; Substrate (aquarium); Residue (chemistry)","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00004937916,0.0003781448,0.0006314274,0.0003424014,0.00009220566,0.00003524642,0.0002413753,0.0002033085,0.0005304383],"category_scores_gemma":[0.000003273227,0.0004378301,0.00009748324,0.0004305284,0.00005899133,0.0009553041,0.00004377812,0.0002403003,0.00001181787],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000391572,"about_ca_system_score_gemma":0.0004910773,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002068167,"about_ca_topic_score_gemma":0.00008556021,"domain_scores_codex":[0.9985405,0.00009996444,0.000433124,0.0004356048,0.0002181763,0.0002726579],"domain_scores_gemma":[0.9992064,0.00008906781,0.0003191571,0.0002099562,0.00006419389,0.0001112481],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003456107,0.0006822539,0.4768509,0.0007135244,0.0009308939,0.00002320989,0.02568883,0.000006612073,0.4779489,0.0002392978,0.000182113,0.01327733],"study_design_scores_gemma":[0.0007760712,0.00004492992,0.3183725,0.0003220759,0.0000371248,7.116786e-9,0.00134457,0.00001068347,0.6773537,0.00001451367,0.001373301,0.000350513],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978718,0.000009064053,0.0001474362,0.0001686587,0.0001849745,0.0005084333,0.000622174,0.00003007465,0.0004573969],"genre_scores_gemma":[0.9939719,0.0001622981,0.001631038,0.000006413762,0.00003559161,0.000003563669,0.002988775,0.000041437,0.001158966],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1994048,"threshold_uncertainty_score":0.9998074,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005571248516021095,"score_gpt":0.1787677898585553,"score_spread":0.1731965413425342,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}