{"id":"W7058484019","doi":"","title":"Nanostructured Lipid Carriers for the delivery of Idebenone in Autosomal Recessive Spastic Ataxia of Charlevoix-Saguenay","year":2020,"lang":"en","type":"article","venue":"Electronic Theses and Dissertations Repository (University of Pisa)","topic":"Magnetic Field Sensors Techniques","field":"Engineering","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Idebenone; Ataxia; Gene; Gene delivery; Antioxidant; Mitochondrion; Disease gene identification; Mutation","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001116483,0.000128799,0.0002206775,0.0001479087,0.00006629377,0.0001529634,0.0001053684,0.0002276327,0.0003008532],"category_scores_gemma":[0.00009991098,0.00005501425,0.0001097882,0.00006455618,0.0000908244,0.0001338844,0.000103437,0.0001683138,0.00008457812],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001487858,"about_ca_system_score_gemma":0.0001183765,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004302982,"about_ca_topic_score_gemma":0.0008012879,"domain_scores_codex":[0.9999545,0.00001013577,0.000003210377,0.000009001578,0.00001613895,0.000007086704],"domain_scores_gemma":[0.9999704,0.000006809589,0.000008050107,0.000001450751,0.000007831482,0.00000532103],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001733288,0.00002391202,0.00007826047,0.00006357788,0.000004072002,0.0001015103,0.00001524314,0.0001359891,0.9959336,0.0000435426,0.00002271215,0.003404325],"study_design_scores_gemma":[0.00004058862,0.001534352,0.001827886,0.0000176198,0.00003328069,0.0005042063,0.00003397142,0.00113684,0.9912916,0.00003838227,0.003534359,0.000006990511],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9918508,0.0050717,0.002138986,0.00006109268,0.00003282892,0.00003718014,0.00005956779,0.00001802887,0.0007297936],"genre_scores_gemma":[0.9930917,0.002322318,0.003121611,0.00003123956,0.000005731658,0.0000319333,0.00006891144,0.000005516388,0.001321053],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.9995697,"threshold_uncertainty_score":0.001079559,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005760226203365558,"score_gpt":0.1851037367650123,"score_spread":0.1793435105616467,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}