{"id":"W7065393116","doi":"","title":"Development of 3D epidermal models: towards the development of a skin model for studies of the autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS)","year":2023,"lang":"pt","type":"dissertation","venue":"Repositório da Universidade de Lisboa (University of Lisbon)","topic":"Particle Detector Development and Performance","field":"Physics and Astronomy","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Animal model; Ataxia; Model system; Mutation; Genetic model","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001278752,0.0005713803,0.0004182583,0.0006893107,0.0004529874,0.001350388,0.0006730597,0.001212949,0.00198185],"category_scores_gemma":[0.0004225131,0.0005953449,0.001035671,0.0003968244,0.000462167,0.001008519,0.0007489327,0.001400153,0.000807888],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006163436,"about_ca_system_score_gemma":0.0008897078,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002223753,"about_ca_topic_score_gemma":0.004096961,"domain_scores_codex":[0.9996006,0.00007044022,0.00002631222,0.00007139544,0.0001867364,0.00004459248],"domain_scores_gemma":[0.9995426,0.00009652981,0.00006849997,0.0001088966,0.0001082234,0.00007530356],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001303734,0.0001391663,0.0006834861,0.0002330072,0.00004076606,0.0003571022,0.0001877155,0.003088179,0.9816386,0.002293685,0.0007044352,0.01050351],"study_design_scores_gemma":[0.00005792555,0.0006103358,0.006522836,0.0001619598,0.0001600844,0.001791021,0.0002600156,0.01481085,0.9334435,0.0008985167,0.04122199,0.00006073418],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.5308136,0.007408119,0.4382243,0.001153704,0.0007396185,0.0007683118,0.003487254,0.001604711,0.01580028],"genre_scores_gemma":[0.6995849,0.006013147,0.2725165,0.0003561068,0.00003238361,0.0007227256,0.002344599,0.0005129523,0.01791674],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002223753,"threshold_uncertainty_score":0.006762803,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0548716765396848,"score_gpt":0.2656143721136999,"score_spread":0.2107426955740151,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}