{"id":"W7070457757","doi":"","title":"Optimization and Mechanistic Exploration of Intravenous Human Immunoglobulin G for Treatment of Traumatic Cervical Spinal Cord Injury","year":2021,"lang":"","type":"dissertation","venue":"TSpace","topic":"Genetics, Bioinformatics, and Biomedical Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"University of Toronto; Stem Cell Network","keywords":"Spinal cord injury; Immune system; Immunosuppression; Inflammation; Neurovascular bundle; Antibody; Dosing; Mechanism (biology)","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002720755,0.0004155211,0.0007912095,0.000166127,0.0001575431,0.00004937101,0.0002053906,0.0006753738,0.000086475],"category_scores_gemma":[0.0002182398,0.0004043473,0.0002394368,0.0001737528,0.000243314,0.00001070364,0.00006218896,0.0000887897,0.000001175273],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006923142,"about_ca_system_score_gemma":0.0004622007,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001327851,"about_ca_topic_score_gemma":0.0001047254,"domain_scores_codex":[0.9975231,0.0001119128,0.001097264,0.0004636607,0.0004270887,0.0003770221],"domain_scores_gemma":[0.9978295,0.00004325301,0.0007089031,0.0004354997,0.0007989757,0.0001838971],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.007418935,0.002156373,0.00001768633,0.00932505,0.0008553109,0.000003815304,0.008458709,0.0004444471,0.7981927,0.0004839656,0.00005236639,0.1725906],"study_design_scores_gemma":[0.003340232,0.06449189,0.00033088,0.0008671395,0.0007401352,0.00001026335,0.0280716,0.01219006,0.8881585,0.0004434228,0.000640843,0.0007150031],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8322679,0.005047239,0.1590812,0.0001686585,0.0004737939,0.002410234,0.0002551893,0.000008572601,0.0002872185],"genre_scores_gemma":[0.9666725,0.01158584,0.0132231,0.00001240117,0.0001683189,0.0001291784,0.00718423,0.00004586767,0.0009785861],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1718756,"threshold_uncertainty_score":0.9998409,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04581588673365288,"score_gpt":0.3793922243474245,"score_spread":0.3335763376137716,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}