{"id":"W7070457757","doi":"","title":"Optimization and Mechanistic Exploration of Intravenous Human Immunoglobulin G for Treatment of Traumatic Cervical Spinal Cord Injury","year":2021,"lang":"","type":"dissertation","venue":"TSpace","topic":"Genetics, Bioinformatics, and Biomedical Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"University of Toronto; Stem Cell Network","keywords":"Spinal cord injury; Immune system; Immunosuppression; Inflammation; Neurovascular bundle; Antibody; Dosing; Mechanism (biology)","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003605832,0.0003185977,0.0004263302,0.0005062312,0.0001247691,0.0007241868,0.0004346371,0.0003683964,0.001092069],"category_scores_gemma":[0.0002598438,0.0001298309,0.0005270113,0.0002311868,0.0002226113,0.0003770771,0.0002879435,0.0007712976,0.0002866173],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003543296,"about_ca_system_score_gemma":0.0006938729,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005926436,"about_ca_topic_score_gemma":0.001032466,"domain_scores_codex":[0.9998353,0.0000357646,0.00001043259,0.0000206269,0.00005635385,0.00004140604],"domain_scores_gemma":[0.9999501,0.0000081492,0.00001699873,0.000003208135,0.00001168958,0.000009826156],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00137931,0.001354125,0.001745113,0.003865777,0.0002127309,0.0004770932,0.0001682896,0.003811046,0.7602565,0.00509775,0.004169329,0.2174629],"study_design_scores_gemma":[0.0006409934,0.01801956,0.0121565,0.001028835,0.0009947006,0.001919452,0.0003013665,0.01098549,0.7297482,0.002825661,0.2213018,0.00007752874],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.767925,0.1757587,0.03321857,0.005116802,0.0008264674,0.0009887106,0.0008765917,0.0003015699,0.0149877],"genre_scores_gemma":[0.8625851,0.1078236,0.02132168,0.001161602,0.0002023493,0.0004853171,0.0005639595,0.00004729741,0.005809209],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001092069,"threshold_uncertainty_score":0.003653347,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04581588673365288,"score_gpt":0.3793922243474245,"score_spread":0.3335763376137716,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}