{"id":"W7070934363","doi":"","title":"Regulation of nuclear factor kappa B subunit c-Rel through phosphorylation by two IKK-related kinases, IKK epsilon and TBK-1","year":2005,"lang":"en","type":"dissertation","venue":"eScholarship@McGill (McGill)","topic":"NF-κB Signaling Pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Transactivation; Phosphorylation; Transcription factor; Phosphorylation cascade; Kinase; Serine; Nuclear transport; IκB kinase; Reporter gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0004262525,0.0008385109,0.0007204749,0.0001866277,0.0005681255,0.00006357564,0.0004630989,0.001463539,0.0002258677],"category_scores_gemma":[0.0003589172,0.0009608346,0.0003001659,0.0003416391,0.0001309412,0.00008707792,0.0001319407,0.0008381639,0.00006804713],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002248673,"about_ca_system_score_gemma":0.00006719377,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003932086,"about_ca_topic_score_gemma":0.0004785104,"domain_scores_codex":[0.9960471,0.0003085889,0.001121552,0.001292373,0.0006504182,0.0005799537],"domain_scores_gemma":[0.997239,0.00006773905,0.00110713,0.0008701743,0.000499221,0.0002167352],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004211824,0.000188312,0.0000734787,0.0001747889,0.0002473208,0.000004422276,0.00002624315,0.00009965699,0.975164,0.004652871,0.00007040989,0.01887732],"study_design_scores_gemma":[0.001845434,0.0004486655,0.00247123,0.0003242198,0.0002611519,0.00001909368,0.0001477559,0.00006322547,0.9382583,0.002263489,0.0527724,0.001125043],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9851523,0.002117165,0.000001053039,0.0000156294,0.0005252101,0.0007284372,0.001491581,0.0001417834,0.009826809],"genre_scores_gemma":[0.9851137,0.0007536278,0.0007439575,0.0001158153,0.00007193857,0.00003707776,0.009423876,0.0003534134,0.003386526],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05270199,"threshold_uncertainty_score":0.9998327,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01038901107784975,"score_gpt":0.2343846487268134,"score_spread":0.2239956376489637,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}