{"id":"W7072120872","doi":"","title":"Using Chemical Crosslinking and Mass Spectrometry for \\nProtein Model Validation and Fold Recognition","year":2006,"lang":"en","type":"dissertation","venue":"UWSpace (University of Waterloo)","topic":"Prenatal Screening and Diagnostics","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Blackberry (Canada); University of Waterloo","funders":"","keywords":"Mass spectrometry; Protein structure; Lysine; Sequence (biology); Phosphoglycerate kinase; Yeast; Molecular model; Protein sequencing; Fold (higher-order function)","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003113309,0.000971989,0.0004927745,0.001039886,0.0007012787,0.001237144,0.0009540088,0.0009032303,0.002679061],"category_scores_gemma":[0.002497845,0.0003866605,0.0007188504,0.0005722067,0.0004582593,0.001141681,0.0006917356,0.001170251,0.001572491],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006930091,"about_ca_system_score_gemma":0.0004581465,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006038749,"about_ca_topic_score_gemma":0.0005356679,"domain_scores_codex":[0.9985694,0.0003466968,0.00013273,0.0004149993,0.0004749302,0.00006119005],"domain_scores_gemma":[0.9985929,0.0004107166,0.0002631109,0.0004405401,0.0002595634,0.00003326384],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001362987,0.0001171604,0.001209716,0.0001463994,0.00005994225,0.0001609314,0.0001003433,0.003878362,0.9683381,0.002151946,0.0005039864,0.02319681],"study_design_scores_gemma":[0.0000149114,0.0001120759,0.001604267,0.00001907328,0.00002768775,0.0002026124,0.00004566518,0.02574918,0.9629936,0.001198506,0.007999943,0.0000325184],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.3774761,0.001063499,0.6063981,0.0004196702,0.0002889629,0.0003453493,0.002120639,0.005471815,0.006415813],"genre_scores_gemma":[0.4638844,0.001529773,0.5229847,0.000286408,0.0000495458,0.0004533119,0.005379564,0.001194651,0.004237574],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.003113309,"threshold_uncertainty_score":0.01646495,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02946095983749118,"score_gpt":0.2483827634402688,"score_spread":0.2189218036027777,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}