{"id":"W7073549997","doi":"","title":"Characterization of human DHRS6, an orphan short chain dehydrogenase/reductase enzyme: a novel, cytosolic type 2 R-beta-hydroxybutyrate dehydrogenase","year":2006,"lang":"en","type":"article","venue":"Oxford University Research Archive (ORA) (University of Oxford)","topic":"Nuclear Structure and Function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Albert-Ludwigs-Universität Freiburg; Universität Heidelberg; Canadian Institutes of Health Research; Genome Canada; Ontario Innovation Trust; Wellcome Trust; GlaxoSmithKline","keywords":"Cytosol; Active site; Mitochondrial matrix; Ketone bodies; Binding site; Dehydrogenase; Enzyme; Substrate (aquarium); Plasma protein binding","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004973738,0.0002641042,0.0003522774,0.0004881526,0.0006577713,0.00002208529,0.0007634759,0.0002300113,0.0001287014],"category_scores_gemma":[0.00002305516,0.000337205,0.0002064421,0.0006892422,0.0007268558,0.00009012046,0.0005044068,0.0003206614,0.000004295811],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008084848,"about_ca_system_score_gemma":0.0002479763,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008057183,"about_ca_topic_score_gemma":0.001824929,"domain_scores_codex":[0.9977164,0.0003583083,0.0002113384,0.0006510781,0.0004682722,0.0005946638],"domain_scores_gemma":[0.9983905,0.00002644292,0.0001858193,0.0006700869,0.0004492426,0.0002779278],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00131383,0.0003447383,0.00262044,0.0000570324,0.0001386615,0.0000577415,0.0002419131,0.00009360843,0.9916007,0.002540532,0.0004354112,0.0005553843],"study_design_scores_gemma":[0.003242477,0.004073463,0.02246934,0.00007430341,0.0002100038,0.00005971772,0.002718585,0.002293409,0.8093414,0.0005274389,0.1540902,0.0008996304],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9919449,0.00002751816,0.003709633,0.00008331271,0.00006300593,0.0004095767,0.0005716569,0.00003213085,0.00315825],"genre_scores_gemma":[0.9937968,0.0002843727,0.001098899,0.00001628091,0.0001351069,2.465163e-7,0.003146232,0.00003596931,0.001486075],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1822593,"threshold_uncertainty_score":0.999908,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01856781620722259,"score_gpt":0.2447818984217448,"score_spread":0.2262140822145222,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}