{"id":"W7073549997","doi":"","title":"Characterization of human DHRS6, an orphan short chain dehydrogenase/reductase enzyme: a novel, cytosolic type 2 R-beta-hydroxybutyrate dehydrogenase","year":2006,"lang":"en","type":"article","venue":"Oxford University Research Archive (ORA) (University of Oxford)","topic":"Nuclear Structure and Function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Albert-Ludwigs-Universität Freiburg; Universität Heidelberg; Canadian Institutes of Health Research; Genome Canada; Ontario Innovation Trust; Wellcome Trust; GlaxoSmithKline","keywords":"Cytosol; Active site; Mitochondrial matrix; Ketone bodies; Binding site; Dehydrogenase; Enzyme; Substrate (aquarium); Plasma protein binding","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009870191,0.0002288124,0.0001837811,0.0001573603,0.00007106431,0.0001946884,0.0001254623,0.0001802485,0.0008693011],"category_scores_gemma":[0.0001927923,0.00005687286,0.0002121753,0.0001561377,0.00009248346,0.00011334,0.00008090705,0.0001411609,0.0006362131],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001149161,"about_ca_system_score_gemma":0.0001074953,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005346516,"about_ca_topic_score_gemma":0.0003816492,"domain_scores_codex":[0.9999499,0.000005663728,0.000004970193,0.00001775165,0.00001492749,0.000006801889],"domain_scores_gemma":[0.9999062,0.0000120744,0.00001634571,0.00001245824,0.00001872064,0.00003418061],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002133584,0.00001744122,0.002331418,0.00005984614,0.00001141079,0.0002881084,0.00003254591,0.00009614156,0.9928525,0.00006631747,0.00009410801,0.003936761],"study_design_scores_gemma":[0.00005909498,0.0008640797,0.08138558,0.00002009754,0.0000628709,0.009738272,0.0001347563,0.003334905,0.8772407,0.0001725227,0.02696837,0.00001879829],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9891948,0.002408911,0.005363537,0.0001672104,0.00003146604,0.00004329499,0.001771303,0.00006844636,0.0009509989],"genre_scores_gemma":[0.9762509,0.00159865,0.00923807,0.0001086795,0.0000451361,0.00002228564,0.009689552,0.00002372692,0.003022979],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008693011,"threshold_uncertainty_score":0.002908111,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01856781620722259,"score_gpt":0.2447818984217448,"score_spread":0.2262140822145222,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}