{"id":"W7073733815","doi":"","title":"Inhibition of Autophagy Promotes the Elimination of Liver Cancer Stem Cells by CD133 Aptamer-Targeted Delivery of Doxorubicin","year":2022,"lang":"en","type":"article","venue":"UWA Profiles and Research Repository (UWA)","topic":"Photonic Crystal and Fiber Optics","field":"Engineering","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre for Global Health Research","funders":"","keywords":"Doxorubicin; Cancer stem cell; Liver cancer; Autophagy; Stem cell; Cancer cell; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008374914,0.0001702267,0.0001545252,0.0001341506,0.00008081136,0.0001378749,0.00006764841,0.0001327383,0.0005508253],"category_scores_gemma":[0.00007597943,0.00009394717,0.0001266424,0.00006927175,0.0001353196,0.0001286206,0.0001118571,0.000220574,0.0001330848],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002334675,"about_ca_system_score_gemma":0.0002042818,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006916618,"about_ca_topic_score_gemma":0.001479198,"domain_scores_codex":[0.9999312,0.00001035613,0.000005108134,0.00001554221,0.00001955189,0.00001825381],"domain_scores_gemma":[0.9999673,0.000008321794,0.000008420933,0.000003088787,0.000005069005,0.00000763227],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004668655,0.00001785541,0.00007723238,0.00001885027,0.000001918842,0.00001999815,0.00001218963,0.0001348816,0.9978823,0.0001074366,0.00006054608,0.001620111],"study_design_scores_gemma":[0.000009706958,0.0001154359,0.0007770594,0.000002263467,0.000003853105,0.00003977538,0.000005346172,0.001611396,0.9965099,0.00002266562,0.0009002736,0.000002372187],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9932594,0.0008876121,0.004172289,0.00009388513,0.00001992191,0.00003111528,0.00006515295,0.00009125591,0.001379456],"genre_scores_gemma":[0.9954036,0.000455023,0.002574753,0.00004492141,0.000005546204,0.00003324195,0.00006103685,0.00001085361,0.001410941],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006916618,"threshold_uncertainty_score":0.001842737,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01778071120165188,"score_gpt":0.2409903205491706,"score_spread":0.2232096093475188,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}