{"id":"W7073737335","doi":"","title":"Contribution of the PALB2 c.2323C>T [p.Q775X] founder mutation in well-defined breast and/or ovarian cancer families and unselected ovarian cancer cases of French Canadian descent.","year":2013,"lang":"en","type":"article","venue":"Apollo (University of Cambridge)","topic":"High-pressure geophysics and materials","field":"Earth and Planetary Sciences","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"PALB2; Ovarian cancer; Breast cancer; Serous fluid; BRCA mutation; Cancer; Founder effect","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004781195,0.0009083382,0.0003546547,0.002954045,0.002202248,0.0006963786,0.001054392,0.001039503,0.003346581],"category_scores_gemma":[0.00231264,0.0004653102,0.0005271686,0.001720897,0.001008068,0.0001665078,0.0007974204,0.0004355899,0.0002657869],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003747515,"about_ca_system_score_gemma":0.003507079,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_topic_score_codex":0.6656486,"about_ca_topic_score_gemma":0.5840568,"domain_scores_codex":[0.9990915,0.00007595425,0.00005780544,0.0002215769,0.0002396104,0.0003135957],"domain_scores_gemma":[0.9990114,0.0001956331,0.0002473885,0.00005896027,0.0001979988,0.0002885994],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0003679653,0.00003851004,0.98022,0.00003148288,0.0001029372,0.01126958,0.000812749,0.0001064471,0.003779338,0.00009906267,0.0003342876,0.002837714],"study_design_scores_gemma":[0.000022606,0.00008713483,0.9809306,0.00002188948,0.0001006298,0.01624897,0.0008432191,0.0002147575,0.0004301098,0.00005561058,0.001027248,0.00001725005],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.998464,0.0004137081,0.00004162629,0.00005088684,0.000006310648,0.00001340716,0.0003194819,0.000004784082,0.0006857876],"genre_scores_gemma":[0.9991485,0.0001807344,0.00008605815,0.00002937098,0.000006457729,0.000006437414,0.0003445707,0.000003813812,0.000194184],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3343514,"threshold_uncertainty_score":0.6726408,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006900293882102506,"score_gpt":0.1774747136789222,"score_spread":0.1705744197968197,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}