{"id":"W7073994285","doi":"","title":"Penetrance of Colorectal Cancer among MLH1/MSH2 Carriers Participating in the Colorectal Cancer Familial Registry in Ontario","year":2009,"lang":"en","type":"article","venue":"Scholarship@Western (Western University)","topic":"Geological and Geochemical Analysis","field":"Earth and Planetary Sciences","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Lynch syndrome; MLH1; Colorectal cancer; Penetrance; MSH2; Population; Cancer registry; DNA mismatch repair","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004694506,0.0001923437,0.0002313659,0.0008340874,0.0008283593,0.0004038806,0.0005073444,0.0002019768,0.001803722],"category_scores_gemma":[0.001726345,0.0002856129,0.0002713413,0.001373392,0.0003427949,0.0001614084,0.0004478882,0.0001688904,0.0001597058],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.005417084,"about_ca_system_score_gemma":0.005116408,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_topic_score_codex":0.9205064,"about_ca_topic_score_gemma":0.9407765,"domain_scores_codex":[0.9994335,0.00006279336,0.00003698845,0.0001247199,0.0001804991,0.0001616158],"domain_scores_gemma":[0.9987036,0.0001468698,0.0005227317,0.0001027858,0.0003145158,0.0002094571],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.000031515,0.000004381255,0.9981701,0.000009694762,0.00001397194,0.0001271345,0.0003483374,0.00003946579,0.000278603,0.00001768986,0.0002322557,0.0007267789],"study_design_scores_gemma":[0.000002614652,0.000008555449,0.9994283,0.000002975685,0.00000735985,0.00008769055,0.0001665125,0.00006176236,0.00003204766,0.000004376256,0.0001957928,0.000001860904],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975367,0.00009175996,0.00007104305,0.00003827913,0.000001396453,0.00001249712,0.001614222,0.00000632153,0.0006277949],"genre_scores_gemma":[0.998588,0.0000849716,0.00005803275,0.00000860306,0.00000105862,0.000007771631,0.0009322471,0.000002502516,0.0003168198],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07949358,"threshold_uncertainty_score":0.1599234,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05451743254526419,"score_gpt":0.2710475032343892,"score_spread":0.216530070689125,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}