{"id":"W7074142324","doi":"","title":"17BIPHE2, an engineered cathelicidin antimicrobial peptide with low susceptibility to proteases, is an effective spermicide and microbicide against Neisseria gonorrhoeae","year":2022,"lang":"en","type":"article","venue":"NOVA (University of Newcastle Australia)","topic":"High-pressure geophysics and materials","field":"Earth and Planetary Sciences","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Spermicide; Cathelicidin; Neisseria gonorrhoeae; Sperm; In vivo; Antimicrobial; Sperm motility; Peptide; In vitro","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002530425,0.0002296843,0.000357018,0.0001256366,0.0003294927,0.00004987466,0.0003761588,0.00006210956,0.002592971],"category_scores_gemma":[0.000006133949,0.0002546532,0.00005838134,0.0003068763,0.000124124,0.0004404285,0.00007930807,0.0001688745,0.00005149162],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002335808,"about_ca_system_score_gemma":0.00006312502,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0438139,"about_ca_topic_score_gemma":0.01517601,"domain_scores_codex":[0.998638,0.0001625558,0.0001446404,0.000556863,0.0001246689,0.0003732898],"domain_scores_gemma":[0.9991052,0.00002925212,0.0001204938,0.0003925556,0.00008019716,0.0002723734],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001625702,0.0003229576,0.03801563,0.0001586969,0.0001236927,0.00009503505,0.007796363,0.01872954,0.9260044,0.00002069743,0.002020041,0.005087324],"study_design_scores_gemma":[0.002604471,0.004117191,0.9294562,0.00008797782,0.0001819352,0.0001136551,0.005476729,0.001254338,0.04981543,0.00005585049,0.00563117,0.001205036],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971493,0.000005859049,0.00006579699,0.0001678529,0.0001414394,0.0007993568,0.001547283,0.00004156128,0.00008153237],"genre_scores_gemma":[0.9972097,0.000002164592,0.001879935,0.0001220265,0.0000611182,5.677842e-7,0.0003486236,0.000009912916,0.0003659898],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8914406,"threshold_uncertainty_score":0.9999906,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02983294283039603,"score_gpt":0.2315700091804193,"score_spread":0.2017370663500233,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}