{"id":"W7074142324","doi":"","title":"17BIPHE2, an engineered cathelicidin antimicrobial peptide with low susceptibility to proteases, is an effective spermicide and microbicide against Neisseria gonorrhoeae","year":2022,"lang":"en","type":"article","venue":"NOVA (University of Newcastle Australia)","topic":"High-pressure geophysics and materials","field":"Earth and Planetary Sciences","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Spermicide; Cathelicidin; Neisseria gonorrhoeae; Sperm; In vivo; Antimicrobial; Sperm motility; Peptide; In vitro","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004368742,0.0001842367,0.0002719699,0.00008598172,0.0001067605,0.0002623799,0.0001803152,0.000462367,0.001157613],"category_scores_gemma":[0.0003332813,0.00008613255,0.0001777433,0.00007755741,0.0001812447,0.0001849362,0.0001366186,0.0002112018,0.0001543943],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001982492,"about_ca_system_score_gemma":0.0002199328,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002032449,"about_ca_topic_score_gemma":0.0002797559,"domain_scores_codex":[0.9998531,0.00004706021,0.00001204631,0.00002446019,0.00003848458,0.00002480717],"domain_scores_gemma":[0.9998603,0.00003534784,0.00005191021,0.000008065973,0.00002076158,0.00002355747],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006354079,0.0000928463,0.002411155,0.0003551344,0.00002020191,0.0001310851,0.00001975201,0.0001127344,0.9867344,0.00008127522,0.0001331651,0.009272804],"study_design_scores_gemma":[0.0002000297,0.008161623,0.02154551,0.00008902679,0.0001218764,0.002047646,0.0001477208,0.0008283361,0.9576648,0.0001250041,0.009052946,0.00001557689],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9885587,0.008436371,0.001461587,0.0003625549,0.00003223994,0.00007027453,0.0001698725,0.00001317843,0.0008952264],"genre_scores_gemma":[0.9911555,0.004824171,0.002382455,0.0002880082,0.00003306374,0.00006511236,0.0002369864,0.00000506409,0.001009547],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001157613,"threshold_uncertainty_score":0.003872573,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02983294283039603,"score_gpt":0.2315700091804193,"score_spread":0.2017370663500233,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}