{"id":"W7080189736","doi":"","title":"Circulating inflammatory cytokines and risk of five cancers: a Mendelian randomization analysis","year":2022,"lang":"en","type":"other","venue":"","topic":"Geochemistry and Geologic Mapping","field":"Computer Science","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Medical Research Council; Faculty of Medicine and Health, University of Sydney; Johns Hopkins Bloomberg School of Public Health; St. George's, University of London; Universität Potsdam; National Institute for Health and Care Research; Singapore Institute for Clinical Sciences; Stanley Center for Psychiatric Research, Broad Institute; Agency for Science, Technology and Research; University of Bristol; Oulun Yliopisto; University of Toronto; World Health Organization; Cancer Research UK; University College London; British Heart Foundation; Massachusetts General Hospital; University Hospitals Bristol NHS Foundation Trust; Turun Yliopisto; University of Oxford; Norges Teknisk-Naturvitenskapelige Universitet; Imperial College London; Helsingin Yliopisto; Broad Institute; Johns Hopkins University","keywords":"Mendelian randomization; Lung cancer; Endometrial cancer; Ovarian cancer; Breast cancer; Genome-wide association study; Cancer; Single-nucleotide polymorphism; Inflammation","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.06240898,0.002324532,0.00556206,0.002369353,0.001149891,0.001507633,0.002893099,0.002226656,0.0119842],"category_scores_gemma":[0.08632936,0.001420216,0.01157567,0.002550885,0.001586943,0.001030372,0.001630531,0.002039879,0.00078672],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009882296,"about_ca_system_score_gemma":0.001574914,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003367405,"about_ca_topic_score_gemma":0.001721801,"domain_scores_codex":[0.9144292,0.06898714,0.003026421,0.008789507,0.003303688,0.001464045],"domain_scores_gemma":[0.9428478,0.04099088,0.004057838,0.009997433,0.001440351,0.0006656434],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.1808111,0.001651958,0.3236431,0.006042837,0.2560072,0.006424757,0.00124015,0.05026333,0.01011096,0.03997175,0.01461013,0.1092228],"study_design_scores_gemma":[0.07276877,0.02080381,0.1547469,0.0008638822,0.1766499,0.006657681,0.0004401503,0.4959296,0.004118882,0.04795225,0.01840134,0.0006669412],"study_design_candidate":"simulation_or_modeling","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6309904,0.00758278,0.3430158,0.00141085,0.0006392424,0.006932043,0.004744278,0.00182711,0.002857521],"genre_scores_gemma":[0.8963296,0.0006768286,0.09428257,0.0004076352,0.0001197558,0.005046063,0.001447824,0.0001312867,0.001558418],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06240898,"threshold_uncertainty_score":0.3300541,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006486936494214219,"score_gpt":0.2081042440358612,"score_spread":0.2016173075416469,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}