{"id":"W7080974147","doi":"","title":"Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits","year":2022,"lang":"en","type":"other","venue":"","topic":"Geochemistry and Geologic Mapping","field":"Computer Science","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"FP7 Ideas: European Research Council; National Institutes of Health; Hjartavernd; Medical Research Council; Tartu Ülikool; Diabetes Research and Wellness Foundation; Hrvatska Zaklada za Znanost; Fondation Leenaards; Magnus Bergvalls Stiftelse; Emil Aaltosen Säätiö; Danish Agency for Science and Higher Education; Marcus och Amalia Wallenbergs minnesfond; Högskolan Dalarna; Institut National de la Santé et de la Recherche Médicale; Ministero della Salute; Kuopion Yliopistollinen Sairaala; Turun Yliopistollinen Keskussairaala; Knut och Alice Wallenbergs Stiftelse; Diabetesliitto; Nierstichting; Ministerio de Economía y Competitividad; British Heart Foundation; Bundesministerium für Bildung und Forschung; Ministero dell’Istruzione, dell’Università e della Ricerca; Erasmus Universiteit Rotterdam; National Health and Medical Research Council; Suomen Kulttuurirahasto; Strategiske Forskningsråd; ZonMw; European Science Foundation; Netherlands Heart Institute; Diabetes Fonds; Fondation Leducq; European Regional Development Fund; King's College London; Juvenile Diabetes Research Foundation International; Canadian Institutes of Health Research; Diabetes UK; Healthway; Health and Safety Executive; Cancer Research UK; National Institute for Health and Care Research; Accare; Donald W. Reynolds Foundation; Eli Lilly and Company; Ministère du Développement Économique, de l’Innovation et de l’Exportation; Forsknings- og Innovationsstyrelsen; Fondation de France; Sundhed og Sygdom, Det Frie Forskningsråd; GlaxoSmithKline; Amgen; Erasmus Universitair Medisch Centrum Rotterdam; Landstinget Dalarnas; European Commission; Norwegian Biodiversity Information Centre; Medical Research Council Canada; Juho Vainion Säätiö; American Heart Association; National Human Genome Research Institute; Danmarks Frie Forskningsfond; Interreg; Andrea and Charles Bronfman Philanthropies; John D. and Catherine T. MacArthur Foundation; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; Bristol-Myers Squibb","keywords":"Genome-wide association study; Trait; Obesity; Genetic association; Quantitative trait locus; Gene–environment interaction; Genetic variants; Waist; Body mass index","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003037616,0.001049523,0.001524629,0.002267075,0.0006060587,0.001152275,0.0007389435,0.0006510557,0.003538461],"category_scores_gemma":[0.007874099,0.0004216746,0.005990946,0.0049334,0.0002387556,0.000378315,0.0007396173,0.0006959949,0.0004356142],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002657794,"about_ca_system_score_gemma":0.0006515582,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.007019329,"about_ca_topic_score_gemma":0.01219269,"domain_scores_codex":[0.9979075,0.0008775377,0.0002343554,0.0006044492,0.0002348098,0.0001413422],"domain_scores_gemma":[0.9961986,0.002249062,0.0004647555,0.0007637976,0.000183129,0.0001405696],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.003755518,0.00006708033,0.7499571,0.001874634,0.1962132,0.000773402,0.00009437045,0.001844847,0.004452228,0.0004621252,0.00342889,0.03707654],"study_design_scores_gemma":[0.0006373575,0.0004622613,0.7717961,0.0003269363,0.2082144,0.0009836467,0.00016296,0.005336923,0.002601537,0.002027672,0.007408648,0.00004154705],"study_design_candidate":"meta_analysis","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8507921,0.09754371,0.02682239,0.001781861,0.0004968992,0.00009792031,0.01774682,0.0009320607,0.003786335],"genre_scores_gemma":[0.98531,0.006298133,0.00353559,0.0002302733,0.0001065335,0.0000629351,0.003485757,0.0001126507,0.0008581114],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007019329,"threshold_uncertainty_score":0.01606464,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04749330446428076,"score_gpt":0.261546795546065,"score_spread":0.2140534910817843,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). 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