{"id":"W7081584268","doi":"","title":"Genetic analysis for a shared biological basis between migraine and coronary artery disease","year":2022,"lang":"en","type":"other","venue":"","topic":"Geochemistry and Geologic Mapping","field":"Computer Science","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"U.S. National Library of Medicine; National Institute of Neurological Disorders and Stroke; National Institute of Allergy and Infectious Diseases; National Cancer Institute; National Heart, Lung, and Blood Institute; Universitätsmedizin der Johannes Gutenberg-Universität Mainz; Universitätsklinikum Hamburg-Eppendorf; Canadian Institutes of Health Research; Allergan; Daiichi Sankyo Europe; St. Jude Medical; National Institutes of Health; Janssen Prevention Center; Avera Institute for Human Genetics; Centre for Medical Systems Biology; Paavo Nurmen Säätiö; Tampereen Tuberkuloosisäätiö; Université de Bordeaux; Sydäntutkimussäätiö; Turun Yliopisto; Norges Forskningsråd; Tampereen Yliopisto; Juho Vainion Säätiö; Technische Universität München; Deutsche Forschungsgemeinschaft; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; British Heart Foundation; Háskóli Íslands; Bundesministerium für Bildung und Forschung; Vrije Universiteit Amsterdam; Oulun Yliopisto; Suomen Kulttuurirahasto; ZonMw; Eberhard Karls Universität Tübingen; Universiteit Leiden; United States-Israel Binational Science Foundation; School of Medicine, Stanford University; Institut National de la Santé et de la Recherche Médicale; Fondation Leducq; Institute of Genetics; Agence Nationale de la Recherche; Universität Heidelberg; Karl-Franzens-Universität Graz; University of Bristol; AstraZeneca; European Commission; Kela; University of Leeds; Terveyden ja hyvinvoinnin laitos; Academy of Finland; King's College London; Regeneron Pharmaceuticals; National Institute of Mental Health; Helse Sør-Øst RHF; Telomere Diagnostics; Wellcome Trust; Internationale Stichting Alzheimer Onderzoek; Sanofi; Norges Teknisk-Naturvitenskapelige Universitet; Deutsches Zentrum für Herz-Kreislaufforschung; University of Ottawa; FP7 Health; Imperial College London; Samfundet Folkhälsan; Universität zu Lübeck; Pfizer; Suomen Lääketieteen Säätiö; Boston Scientific Corporation; Medicinska Understödsföreningen Liv och Hälsa; Turun Yliopistollinen Keskussairaala; Helsingin ja Uudenmaan Sairaanhoitopiiri; Foundation for Cardiovascular Research; Medizinische Universität Graz; Emil Aaltosen Säätiö; University of Pennsylvania; Medical Research Council; Institute for Translational Medicine and Therapeutics; Biocenter, University of Oulu; Folkhälsanin Tutkimussäätiö; National Institute for Health and Care Research; Teva Pharmaceutical Industries; Amgen","keywords":"Migraine; Migraine with aura; Coronary artery disease; Genetic association; Aura; Disease; Allele; Pathogenesis","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001134994,0.0002158147,0.0003736272,0.0001815405,0.00008654442,0.00005267155,0.0006108795,0.0001250976,0.009925238],"category_scores_gemma":[0.00006645864,0.0001739347,0.000214936,0.0003738397,0.00005478943,0.00002127684,0.0005349942,0.00009268282,0.000006309191],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000126166,"about_ca_system_score_gemma":0.00002939622,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000213668,"about_ca_topic_score_gemma":0.00001354159,"domain_scores_codex":[0.9986849,0.00005432367,0.0001738467,0.0007157071,0.0001228761,0.0002483574],"domain_scores_gemma":[0.9990115,0.0001508758,0.0001032427,0.000543383,0.00001889607,0.0001721418],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001915949,0.00009897133,0.4969026,0.0001987813,0.001970748,0.0001715705,0.00007267974,0.0000556898,0.00001451406,0.0006418098,0.4875568,0.01229666],"study_design_scores_gemma":[0.0002709675,0.00007929562,0.2583898,0.00001062379,0.000363965,0.000006310153,0.0000152663,0.004829113,0.00000155899,0.001828247,0.7337798,0.0004250693],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"methods","genre_gemma":"other","genre_scores_codex":[0.003579504,0.005273124,0.6327195,0.01071085,0.0002519337,0.002087354,0.00212181,0.001605658,0.3416503],"genre_scores_gemma":[0.07782083,0.0001162019,0.05087256,0.0008605835,0.000327972,0.0003843305,0.001124456,0.00003891462,0.8684542],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.5818469,"threshold_uncertainty_score":0.9909799,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02869954662510616,"score_gpt":0.2328384195673516,"score_spread":0.2041388729422454,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). 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