{"id":"W7081584268","doi":"","title":"Genetic analysis for a shared biological basis between migraine and coronary artery disease","year":2022,"lang":"en","type":"other","venue":"","topic":"Geochemistry and Geologic Mapping","field":"Computer Science","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"U.S. National Library of Medicine; National Institute of Neurological Disorders and Stroke; National Institute of Allergy and Infectious Diseases; National Cancer Institute; National Heart, Lung, and Blood Institute; Universitätsmedizin der Johannes Gutenberg-Universität Mainz; Universitätsklinikum Hamburg-Eppendorf; Canadian Institutes of Health Research; Allergan; Daiichi Sankyo Europe; St. Jude Medical; National Institutes of Health; Janssen Prevention Center; Avera Institute for Human Genetics; Centre for Medical Systems Biology; Paavo Nurmen Säätiö; Tampereen Tuberkuloosisäätiö; Université de Bordeaux; Sydäntutkimussäätiö; Turun Yliopisto; Norges Forskningsråd; Tampereen Yliopisto; Juho Vainion Säätiö; Technische Universität München; Deutsche Forschungsgemeinschaft; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; British Heart Foundation; Háskóli Íslands; Bundesministerium für Bildung und Forschung; Vrije Universiteit Amsterdam; Oulun Yliopisto; Suomen Kulttuurirahasto; ZonMw; Eberhard Karls Universität Tübingen; Universiteit Leiden; United States-Israel Binational Science Foundation; School of Medicine, Stanford University; Institut National de la Santé et de la Recherche Médicale; Fondation Leducq; Institute of Genetics; Agence Nationale de la Recherche; Universität Heidelberg; Karl-Franzens-Universität Graz; University of Bristol; AstraZeneca; European Commission; Kela; University of Leeds; Terveyden ja hyvinvoinnin laitos; Academy of Finland; King's College London; Regeneron Pharmaceuticals; National Institute of Mental Health; Helse Sør-Øst RHF; Telomere Diagnostics; Wellcome Trust; Internationale Stichting Alzheimer Onderzoek; Sanofi; Norges Teknisk-Naturvitenskapelige Universitet; Deutsches Zentrum für Herz-Kreislaufforschung; University of Ottawa; FP7 Health; Imperial College London; Samfundet Folkhälsan; Universität zu Lübeck; Pfizer; Suomen Lääketieteen Säätiö; Boston Scientific Corporation; Medicinska Understödsföreningen Liv och Hälsa; Turun Yliopistollinen Keskussairaala; Helsingin ja Uudenmaan Sairaanhoitopiiri; Foundation for Cardiovascular Research; Medizinische Universität Graz; Emil Aaltosen Säätiö; University of Pennsylvania; Medical Research Council; Institute for Translational Medicine and Therapeutics; Biocenter, University of Oulu; Folkhälsanin Tutkimussäätiö; National Institute for Health and Care Research; Teva Pharmaceutical Industries; Amgen","keywords":"Migraine; Migraine with aura; Coronary artery disease; Genetic association; Aura; Disease; Allele; Pathogenesis","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002797876,0.000482593,0.0004257372,0.001616919,0.0003318818,0.0005893015,0.0005932794,0.0006079832,0.002018363],"category_scores_gemma":[0.0077016,0.0002047986,0.0008394691,0.001443874,0.0007910086,0.0002454638,0.001216438,0.0005444143,0.0001684891],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002547087,"about_ca_system_score_gemma":0.0004377897,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001478961,"about_ca_topic_score_gemma":0.00182495,"domain_scores_codex":[0.9979353,0.0008654172,0.0001704743,0.0004742753,0.0004382859,0.0001162933],"domain_scores_gemma":[0.994767,0.002992769,0.00119034,0.0006164587,0.0002281448,0.0002052756],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0008487114,0.000148097,0.9274167,0.0001359759,0.00214696,0.001249407,0.0002031652,0.002268223,0.0352503,0.00111383,0.0005023574,0.02871612],"study_design_scores_gemma":[0.00009585037,0.0002828158,0.9853237,0.00002359581,0.0004568241,0.001703453,0.00008679144,0.007223405,0.003026514,0.001314214,0.0004431774,0.00001966723],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9897066,0.0004401912,0.008311316,0.0003248674,0.00001257119,0.0000397095,0.0003469563,0.00006801971,0.0007496589],"genre_scores_gemma":[0.9919856,0.0001312804,0.007254137,0.00008906603,0.00003947753,0.00002596975,0.0003474398,0.0000146753,0.0001123535],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002797876,"threshold_uncertainty_score":0.01479673,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02869954662510616,"score_gpt":0.2328384195673516,"score_spread":0.2041388729422454,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). 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