{"id":"W7084617547","doi":"10.1111/cge.14784/v1/review2","title":"Review for \"<i>PMS2</i> c.2117del (p.Lys706Serfs*19) is the Most Frequent Cancer-Associated Founder Pathogenic Variant in the French-Canadian Population of Quebec, Canada\"","year":2025,"lang":"en","type":"peer-review","venue":"","topic":"Psychology of Social Influence","field":"Social Sciences","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"","keywords":"Population; Founder effect; Allele frequency; Haplotype; Mutation; Genetic variation","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","sts","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.005639734,0.0006660123,0.00158443,0.0002292647,0.001390673,0.0001114852,0.002894705,0.0008821297,0.00164284],"category_scores_gemma":[0.003863605,0.0004873488,0.0005634646,0.002455466,0.0005939549,0.0002048312,0.0000958728,0.0008416778,0.00001028205],"about_ca_system_candidate":true,"about_ca_system_consensus":true,"about_ca_system_score_codex":0.005826296,"about_ca_system_score_gemma":0.02410238,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_topic_score_codex":0.9992254,"about_ca_topic_score_gemma":0.9999899,"domain_scores_codex":[0.9925126,0.001905935,0.001739729,0.0009750074,0.001529752,0.001336976],"domain_scores_gemma":[0.9944919,0.001408959,0.001376602,0.001159429,0.001212483,0.0003506191],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000002395443,0.00004906387,0.0001254348,0.001522675,0.0002107142,0.00001289121,0.0009778285,0.000003936912,0.000003280245,0.007356015,0.9837918,0.005943992],"study_design_scores_gemma":[0.0002657853,0.00001822695,0.00907988,0.009473408,0.0006601044,0.000001783684,0.0001624713,0.000008377253,2.470576e-7,0.002998853,0.9768013,0.0005295727],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"review","genre_scores_codex":[0.0001596848,0.3672533,0.00002057976,0.579929,0.003824266,0.006650052,0.003621349,0.00004854198,0.03849319],"genre_scores_gemma":[0.007201216,0.4209414,0.000129174,0.3823364,0.0008355125,0.002968498,0.002011235,0.00009306151,0.1834835],"genre_candidate":"commentary","genre_consensus":null,"teacher_disagreement_score":0.1975926,"threshold_uncertainty_score":0.9999094,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0468940642142722,"score_gpt":0.3524653153322078,"score_spread":0.3055712511179356,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}