{"id":"W7093121815","doi":"","title":"C002 | SUBCUTANEOUS DARATUMUMAB + BORTEZOMIB/LENALIDOMIDE/DEXAMETHASONE WITH DARA + LENALIDOMIDE MAINTENANCE IN TRANSPLANT-ELIGIBLE PATIENTS WITH NDMM: ANALYSIS OF SUSTAINED MINIMAL RESIDUAL DISEASE NEGATIVITY IN THE PHASE 3 PERSEUS TRIAL","year":2025,"lang":"en","type":"article","venue":"DOAJ (DOAJ: Directory of Open Access Journals)","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hotel Dieu Hospital","funders":"","keywords":"Daratumumab; Minimal residual disease; Lenalidomide; Multiple myeloma; Clinical endpoint; Clinical trial; Confidence interval","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002270368,0.0006412618,0.001315172,0.0002105865,0.0002071692,0.001051973,0.000628097,0.0007119071,0.003940437],"category_scores_gemma":[0.001334019,0.0002340584,0.001335569,0.0003528131,0.000614599,0.0005614445,0.0004007037,0.001639965,0.0005633396],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006808476,"about_ca_system_score_gemma":0.001070086,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005759301,"about_ca_topic_score_gemma":0.002234702,"domain_scores_codex":[0.9993587,0.000437588,0.00003595087,0.00006257286,0.00005090603,0.00005432418],"domain_scores_gemma":[0.9990776,0.0002750736,0.0002009754,0.0000798906,0.00004799499,0.0003185337],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9163024,0.009488646,0.007627999,0.0005155334,0.001386478,0.00007581619,0.00006125207,0.001050285,0.006294015,0.0002009379,0.00311105,0.05388549],"study_design_scores_gemma":[0.6504406,0.3145634,0.02585691,0.00007032267,0.001117805,0.0002633538,0.00006242299,0.001316273,0.001874452,0.0003130031,0.004090167,0.00003133068],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9909465,0.003077336,0.0002288037,0.000542833,0.0001644328,0.0009518916,0.001636583,0.00006141365,0.002390246],"genre_scores_gemma":[0.9913781,0.001300327,0.001031192,0.001054517,0.0002477735,0.0006851384,0.002981432,0.00001913202,0.001302334],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003940437,"threshold_uncertainty_score":0.01318204,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1207835791166059,"score_gpt":0.5252448282280195,"score_spread":0.4044612491114136,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}