{"id":"W7098018610","doi":"","title":"Impurity Profiling: Theory and Practice P.Venkatesan and K.Valliappan","year":2015,"lang":"en","type":"article","venue":"","topic":"Analytical Methods in Pharmaceuticals","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Impurity; Active ingredient; Drug; Pharmaceutical industry; Hazardous waste; Pharmaceutical manufacturing","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003409151,0.001254031,0.001583273,0.00480886,0.000901531,0.00538479,0.002419622,0.002714106,0.00625267],"category_scores_gemma":[0.005290715,0.0008276902,0.001340578,0.004410626,0.002792691,0.004597886,0.002167943,0.00268211,0.004683549],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002286995,"about_ca_system_score_gemma":0.002685383,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002368867,"about_ca_topic_score_gemma":0.001392937,"domain_scores_codex":[0.9970745,0.0006124549,0.0002052829,0.0004855579,0.001449936,0.0001722545],"domain_scores_gemma":[0.9961578,0.001728684,0.0002707331,0.0003234274,0.001366066,0.0001532618],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009994491,0.0001766268,0.002659707,0.003703159,0.0001219934,0.0007119597,0.0004488701,0.01259244,0.003667928,0.1821556,0.02983306,0.7638288],"study_design_scores_gemma":[0.00003773966,0.0003241587,0.003187714,0.004164481,0.0001705995,0.004022239,0.0007158534,0.05389354,0.01010532,0.2384785,0.6846335,0.000266466],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"methods","genre_scores_codex":[0.0070324,0.5488452,0.3515069,0.0111002,0.001858302,0.0003311797,0.0004087021,0.001150865,0.07776609],"genre_scores_gemma":[0.1068188,0.6456497,0.2153989,0.002550256,0.001986652,0.0003587806,0.0007695199,0.0003251052,0.02614234],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.00625267,"threshold_uncertainty_score":0.0209173,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.134898213588584,"score_gpt":0.4526641119483818,"score_spread":0.3177658983597977,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}