{"id":"W7098018610","doi":"","title":"Impurity Profiling: Theory and Practice P.Venkatesan and K.Valliappan","year":2015,"lang":"en","type":"article","venue":"","topic":"Analytical Methods in Pharmaceuticals","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Impurity; Active ingredient; Drug; Pharmaceutical industry; Hazardous waste; Pharmaceutical manufacturing","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.002850044,0.0001380407,0.0001809428,0.0000180977,0.00004745503,0.00005816732,0.0001038146,0.0001160147,0.0003343131],"category_scores_gemma":[0.01062949,0.0001110194,0.00002258428,0.00006018621,0.0002715129,0.0001770738,0.0001956,0.0002813989,0.0000190768],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002680297,"about_ca_system_score_gemma":0.00004261235,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007056388,"about_ca_topic_score_gemma":2.478458e-7,"domain_scores_codex":[0.9987867,0.0002744859,0.0001952282,0.0003099709,0.0001977556,0.0002358461],"domain_scores_gemma":[0.9963002,0.002874438,0.00005492161,0.0002267696,0.000104607,0.0004390952],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.001298766,0.0003975958,0.01605538,0.0004120035,0.0002922316,0.00009000443,0.0008345191,0.000001496902,0.077469,0.8409917,0.001820052,0.06033727],"study_design_scores_gemma":[0.002484599,0.0001097915,0.0002109006,0.00005318292,0.0005199081,0.0005439258,0.007258315,0.003922767,0.3779939,0.4998091,0.1062468,0.0008468748],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":"theoretical_or_conceptual","genre_codex":"other","genre_gemma":"empirical","genre_scores_codex":[0.1784682,0.002625791,0.01430595,0.002841056,0.0000947748,0.000175999,0.000007105335,0.0003062821,0.8011749],"genre_scores_gemma":[0.7608086,0.0002248515,0.2309755,0.001701506,0.0002410395,0.0000156281,0.000002743424,0.00003808973,0.005991975],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.7951829,"threshold_uncertainty_score":0.9977044,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.134898213588584,"score_gpt":0.4526641119483818,"score_spread":0.3177658983597977,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}