{"id":"W7104251783","doi":"10.5281/zenodo.17538639","title":"Needleless Self-Administration of Vaccines via Mucosal (Rectal) Thermo-/Mucoadhesive Gels: A Mathematical, Biological, and Chemical Overview","year":2025,"lang":"en","type":"article","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"Advanced Drug Delivery Systems","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"","keywords":"Biocompatible material; Mucus; Good laboratory practice; Compliance (psychology); Conceptual model; Mucosal immunity","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0006458971,0.0001776337,0.0002863513,0.0001425899,0.0006307786,0.00008619158,0.0004812644,0.0001981869,0.004682854],"category_scores_gemma":[0.0004297443,0.0001637953,0.00005800196,0.0004189618,0.0002157587,0.0001348373,0.0005559745,0.0003371954,0.0006845816],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008089747,"about_ca_system_score_gemma":0.00000902096,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001808721,"about_ca_topic_score_gemma":1.004521e-7,"domain_scores_codex":[0.9981659,0.0006248002,0.0004208131,0.0003561521,0.0001472309,0.0002851235],"domain_scores_gemma":[0.998874,0.0001923111,0.0001717261,0.0002444964,0.0003823895,0.0001350891],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001360759,0.001923743,0.0001140187,0.001540292,0.0007254111,0.00005862043,0.003777128,0.00005747639,0.6521426,0.02944963,0.03359456,0.2752558],"study_design_scores_gemma":[0.002103816,0.0005645585,0.0005781187,0.0001367805,0.0001681037,0.0003396807,0.001118327,0.004365806,0.09626435,0.0037483,0.8901681,0.0004440791],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9539886,0.001605084,0.004956565,0.0009521405,0.000206571,0.001216737,0.0001839266,0.0006314111,0.03625895],"genre_scores_gemma":[0.9980524,0.000677732,0.0003848854,0.0002022089,0.00007100436,3.238874e-7,0.0002083233,0.0002150774,0.0001880478],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8565735,"threshold_uncertainty_score":0.996227,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1053735556632249,"score_gpt":0.3814127308752064,"score_spread":0.2760391752119815,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}