{"id":"W7106489475","doi":"10.17632/trjgk9nmrk.1","title":"Tri-Functional CRISPR Screen Reveals Overexpression of QDR2 and QDR3 Transporters Increase Fumaric Acid Production in Kluyveromyces marxianus","year":2025,"lang":"","type":"dataset","venue":"Mendeley Data","topic":"","field":"","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Concordia University","funders":"","keywords":"Kluyveromyces marxianus; Fumaric acid; CRISPR; Yeast; Transporter; Kluyveromyces","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001315188,0.002499538,0.002471209,0.004098691,0.001779572,0.002469568,0.003077698,0.002243403,0.1075811],"category_scores_gemma":[0.006183696,0.0009502898,0.001925834,0.006774353,0.0005041718,0.001220357,0.002117965,0.001985569,0.07127762],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001943717,"about_ca_system_score_gemma":0.005668016,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.02231297,"about_ca_topic_score_gemma":0.03874622,"domain_scores_codex":[0.9982378,0.0001570772,0.000185987,0.0004434664,0.00060304,0.0003725332],"domain_scores_gemma":[0.996565,0.001172153,0.0005197972,0.0005468738,0.0007944236,0.0004017384],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007357608,0.0001058379,0.002881387,0.005516091,0.0003504907,0.0001200811,0.00009126309,0.0008985046,0.00607692,0.001047796,0.9774626,0.004713137],"study_design_scores_gemma":[0.001818281,0.000201601,0.02190232,0.001033912,0.0004232228,0.0001524995,0.0001425935,0.0008527866,0.007767136,0.002154513,0.9633633,0.00018774],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"dataset","genre_gemma":"dataset","genre_scores_codex":[0.0001992673,0.00003592547,0.00003677903,0.00003147855,0.00001487343,0.00001038862,0.9989821,0.0002755068,0.0004135491],"genre_scores_gemma":[0.0005944153,0.00005977767,0.0002619646,0.00004650653,0.000003547353,0.00007792294,0.998264,0.0001155137,0.0005763692],"genre_candidate":"dataset","genre_consensus":"dataset","teacher_disagreement_score":0.1075811,"threshold_uncertainty_score":0.3598946,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04779168972323181,"score_gpt":0.2936826512155556,"score_spread":0.2458909614923238,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}