{"id":"W7108206913","doi":"10.1681/asn.2025swp337ha","title":"Dapagliflozin Treatment Induces Alternate RAAS Activation in Stable Kidney Transplant Recipients","year":2025,"lang":"en","type":"article","venue":"Journal of the American Society of Nephrology","topic":"Diabetes Treatment and Management","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; St. Paul's Hospital; University Health Network; University of British Columbia","funders":"","keywords":"Dapagliflozin; Kidney; Kidney disease; Kidney transplantation; Kidney transplant; Urinary system; Diabetes mellitus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002511051,0.0002198695,0.0007609944,0.0001595456,0.0001221735,0.0004983349,0.000174922,0.0002183426,0.00163056],"category_scores_gemma":[0.001655659,0.0001036657,0.0008372586,0.0002059475,0.0003605583,0.0002216295,0.0002232982,0.0006724345,0.0001177037],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002818231,"about_ca_system_score_gemma":0.0003642376,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001977902,"about_ca_topic_score_gemma":0.0003550937,"domain_scores_codex":[0.9992775,0.0003320638,0.00007473948,0.0001127648,0.0001197642,0.00008319769],"domain_scores_gemma":[0.998817,0.0004237644,0.0005122344,0.0000740906,0.00003788031,0.000135086],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.5171641,0.006706527,0.2354318,0.00136295,0.003433686,0.0003201431,0.0002975366,0.001437587,0.08425505,0.0003268826,0.0008179796,0.1484459],"study_design_scores_gemma":[0.02310301,0.1562788,0.7945974,0.0001101291,0.003249031,0.0005461562,0.0001405174,0.003843591,0.01591198,0.0004576769,0.001724076,0.00003774259],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.998461,0.0008818986,0.0002834582,0.00003983297,0.0000122449,0.0000360904,0.00007557132,0.000008885929,0.0002010896],"genre_scores_gemma":[0.9993445,0.0001728483,0.00022447,0.00006087363,0.00001302833,0.000028553,0.00008902231,0.000001636732,0.00006522415],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002511051,"threshold_uncertainty_score":0.01327986,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01782166916279635,"score_gpt":0.2849868287268948,"score_spread":0.2671651595640984,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}