{"id":"W7108441195","doi":"10.1182/blood-2025-252","title":"Tumor clearance, T-cell fitness, and minimal residual disease (MRD) outcomes in patients with relapsed/refractory multiple myeloma (RRMM) treated with cevostamab plus pomalidomide and dexamethasone: Biomarker analyses from CAMMA 1 Arm B","year":2025,"lang":"en","type":"article","venue":"Blood","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; Alberta Cancer Foundation; McMaster University","funders":"","keywords":"Pomalidomide; Multiple myeloma; Biomarker; Dexamethasone; Randomized controlled trial; Clinical endpoint; Lenalidomide; Minimal residual disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00108345,0.0004775775,0.001060273,0.000461008,0.0003202198,0.0007001621,0.0005805381,0.000591608,0.001664879],"category_scores_gemma":[0.001146774,0.0002681073,0.0008729945,0.0004651264,0.0003412689,0.0006094031,0.0005770298,0.001189098,0.0003539143],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007721312,"about_ca_system_score_gemma":0.000595204,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009763016,"about_ca_topic_score_gemma":0.001580463,"domain_scores_codex":[0.9995093,0.0001771383,0.00003781767,0.0001186186,0.00006952178,0.00008766646],"domain_scores_gemma":[0.9989734,0.0001269458,0.0003275069,0.00005474214,0.00006512704,0.0004523624],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.2112749,0.008111683,0.7073994,0.0002767851,0.00163049,0.0002482338,0.0002193839,0.001195802,0.01322216,0.00009931247,0.002333545,0.05398829],"study_design_scores_gemma":[0.01403063,0.07413421,0.9048927,0.00006583667,0.0009689281,0.0004627384,0.0001575476,0.001439006,0.001867971,0.000213891,0.001730204,0.00003627015],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9981074,0.000758339,0.00005693355,0.00009020347,0.00001001555,0.00008972549,0.0005329946,0.000007743098,0.0003465609],"genre_scores_gemma":[0.997795,0.0001915524,0.0001573266,0.0001732429,0.00004674742,0.000123207,0.001237534,0.000003318432,0.0002720266],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001664879,"threshold_uncertainty_score":0.005729914,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01766783666198402,"score_gpt":0.2774876403507092,"score_spread":0.2598198036887252,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}