{"id":"W7108452504","doi":"10.1182/blood-2025-2287","title":"Real-world sequencing of anti-BCMA CAR T-cells and bispecific T-cell engagers in Relapsed/Refractory multiple myeloma: A multi-country analysis","year":2025,"lang":"en","type":"article","venue":"Blood","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hotel Dieu Hospital","funders":"","keywords":"Clinical Practice; CAR T-cell therapy; Clinical trial; Multiple myeloma; Real world data; Daratumumab; Bispecific antibody; Hematologic Neoplasms","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004045424,0.0003633848,0.0008565647,0.00202188,0.0004908036,0.001438618,0.0008438234,0.0007246286,0.001911158],"category_scores_gemma":[0.008418397,0.0004691569,0.001191898,0.00378699,0.0004791209,0.0006084177,0.001316758,0.001055639,0.0004004055],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009488554,"about_ca_system_score_gemma":0.0009846579,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006832838,"about_ca_topic_score_gemma":0.006936625,"domain_scores_codex":[0.9953101,0.001977464,0.0005047674,0.001372859,0.0003868844,0.0004479373],"domain_scores_gemma":[0.9887235,0.003487526,0.00466029,0.001020763,0.001292084,0.0008159193],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0007184283,0.00008541141,0.987171,0.0003488981,0.001122989,0.0002957943,0.0002533187,0.000962009,0.0005289069,0.0002321415,0.00295558,0.005325575],"study_design_scores_gemma":[0.0001183165,0.0003695121,0.9844655,0.0003054565,0.001201637,0.001368006,0.00111184,0.002637662,0.0007237346,0.0002686413,0.007374585,0.00005505875],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9650133,0.002375928,0.001313624,0.0003334457,0.00002440592,0.00007232814,0.03022435,0.00002654055,0.000616182],"genre_scores_gemma":[0.9807544,0.0006251446,0.001341407,0.0003532148,0.00002747419,0.0001003258,0.01660518,0.00003146323,0.0001614805],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006832838,"threshold_uncertainty_score":0.02139449,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02518383271107581,"score_gpt":0.2919276031433316,"score_spread":0.2667437704322558,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}