{"id":"W7108465232","doi":"10.1182/blood-2025-5094","title":"Polyunsaturated fatty acids control lipid membrane dynamics and ferroptosis sensitivity in B-cell lymphoma","year":2025,"lang":"en","type":"article","venue":"Blood","topic":"Ferroptosis and cancer prognosis","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute for Research in Immunology and Cancer","funders":"","keywords":"GPX4; Polyunsaturated fatty acid; Cancer cell; Programmed cell death; Cell culture; Arachidonic acid; Lymphoma; Metabolomics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002157039,0.0002395623,0.0002329023,0.0006182937,0.0001780904,0.0006838786,0.0001974785,0.0002778367,0.001591468],"category_scores_gemma":[0.0003815221,0.0001367368,0.0002348009,0.0004645643,0.00017377,0.0002114307,0.0003112128,0.0003232065,0.0006211311],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005129341,"about_ca_system_score_gemma":0.0002276203,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001878426,"about_ca_topic_score_gemma":0.001707568,"domain_scores_codex":[0.9997832,0.00003009524,0.00002196538,0.0000539109,0.00006672114,0.00004411134],"domain_scores_gemma":[0.9997129,0.0000584605,0.0001114316,0.00002884697,0.00005165664,0.00003669515],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001779948,0.00002720491,0.00523128,0.00005751201,0.00001647337,0.00004143909,0.00001892362,0.000177528,0.9917957,0.00003813523,0.00009020571,0.00232778],"study_design_scores_gemma":[0.00001480828,0.0001804674,0.06655628,0.00002029406,0.00005480239,0.0002537253,0.0001330418,0.00267313,0.9268138,0.00009818095,0.003186975,0.00001448543],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9936661,0.0009545212,0.001352261,0.00006702424,0.000007435655,0.00001725282,0.003016767,0.0001793106,0.0007393173],"genre_scores_gemma":[0.9955248,0.0003730069,0.0008086209,0.00004611579,0.000001990627,0.00001900931,0.00251562,0.00003087781,0.0006799864],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001878426,"threshold_uncertainty_score":0.005324006,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006059158868055167,"score_gpt":0.2273504864810255,"score_spread":0.2212913276129703,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}