{"id":"W7108467264","doi":"10.1158/1538-7445.canevol25-ia007","title":"Abstract IA007: Evolutionary cancer epidemiology","year":2025,"lang":"en","type":"article","venue":"Cancer Research","topic":"Cancer Genomics and Diagnostics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; McMaster University Medical Centre","funders":"","keywords":"Cancer; Somatic evolution in cancer; Population; Cancer incidence; Epidemiology of cancer; Evolutionary dynamics; Cancer cell; Biological evolution","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0047302,0.0008818683,0.0009610266,0.004524811,0.001181211,0.004448897,0.001409344,0.003428172,0.05183608],"category_scores_gemma":[0.02399601,0.0003735003,0.001054831,0.005292505,0.001201974,0.002360529,0.003726151,0.005113686,0.008754586],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00335944,"about_ca_system_score_gemma":0.003596405,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.009070428,"about_ca_topic_score_gemma":0.003939376,"domain_scores_codex":[0.9972876,0.001446275,0.0001156757,0.0004120578,0.0005178546,0.0002204628],"domain_scores_gemma":[0.9874363,0.004518349,0.0008565337,0.0007603032,0.00436524,0.002063228],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.00009253628,0.00003951589,0.0123872,0.0008864412,0.0001431333,0.0001695438,0.0002065178,0.00181258,0.0001683718,0.07288411,0.7529378,0.1582722],"study_design_scores_gemma":[0.0000445141,0.00006574793,0.0189045,0.003207934,0.0001133263,0.0004835346,0.0004044319,0.003274813,0.0001817299,0.09128235,0.8819655,0.00007154152],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"other","genre_scores_codex":[0.008263994,0.1044621,0.03139771,0.6088823,0.04071573,0.0002706469,0.0216941,0.00167764,0.1826358],"genre_scores_gemma":[0.2525995,0.2236204,0.03624015,0.1289275,0.1121703,0.001175296,0.04306666,0.001456838,0.2007433],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.05183608,"threshold_uncertainty_score":0.1734089,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08075432706532724,"score_gpt":0.4528611267341087,"score_spread":0.3721067996687815,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}