{"id":"W7108476913","doi":"10.1182/blood-2025-494","title":"Combined assessment of circulating tumor cells (CTCs) and measurable residual disease (MRD) for dynamic risk assessment of patients (Pts) with multiple myeloma (MM)","year":2025,"lang":"en","type":"article","venue":"Blood","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hotel Dieu Hospital","funders":"","keywords":"Circulating tumor cell; Minimal residual disease; Bone marrow; Multiple myeloma; Immunophenotyping; Clinical trial; Flow cytometry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001085891,0.0002661709,0.0004131322,0.0007783915,0.0001450235,0.0006670433,0.0002754632,0.000323311,0.001025512],"category_scores_gemma":[0.002382313,0.0001193316,0.0002611012,0.0007004507,0.0001147564,0.0003149147,0.0004765922,0.0003854978,0.0002299991],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002645971,"about_ca_system_score_gemma":0.0002381838,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004492634,"about_ca_topic_score_gemma":0.0007073251,"domain_scores_codex":[0.9994093,0.0002173212,0.00006404018,0.0001512547,0.0001187941,0.0000392891],"domain_scores_gemma":[0.9988078,0.00035946,0.0003884716,0.0001255781,0.0001625637,0.0001561116],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002115199,0.0001135432,0.9449121,0.00008161839,0.0001322737,0.0001325487,0.00005551456,0.0008739232,0.005350718,0.00007503881,0.0006397903,0.04551774],"study_design_scores_gemma":[0.0001903423,0.001563476,0.9789291,0.00004410014,0.000239412,0.001533661,0.0001026367,0.008832482,0.005727514,0.000290292,0.002532187,0.00001465087],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9939587,0.001531972,0.002071678,0.0001015066,0.00001564181,0.0000493453,0.001388539,0.00003966338,0.0008428725],"genre_scores_gemma":[0.997236,0.0001629323,0.001368994,0.00002677131,0.00001715455,0.00002693033,0.0009710448,0.000004993293,0.0001853556],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001085891,"threshold_uncertainty_score":0.005742788,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01174581384605436,"score_gpt":0.2997749837798987,"score_spread":0.2880291699338443,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}