{"id":"W7108662280","doi":"10.1182/blood-2025-2187","title":"Light-chain MGUS defined as per the revised definition of the istopmm study: Experience from the university of calgary MGUS clinic","year":2025,"lang":"en","type":"article","venue":"Blood","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Monoclonal gammopathy of undetermined significance; Multiple myeloma; Monoclonal gammopathy; Confidence interval; Lymphoproliferative disorders; Population; Waldenstrom macroglobulinemia; Prospective cohort study","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.005261077,0.0005051413,0.000696358,0.001212693,0.0006679374,0.001109186,0.001140494,0.00060314,0.0007777972],"category_scores_gemma":[0.007120498,0.0002429888,0.000328044,0.003436212,0.00101665,0.0005397355,0.001607983,0.0008633158,0.0002632243],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003367206,"about_ca_system_score_gemma":0.003787121,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.07204854,"about_ca_topic_score_gemma":0.06971788,"domain_scores_codex":[0.9971241,0.001136599,0.0002536381,0.0003936367,0.0006853946,0.0004066084],"domain_scores_gemma":[0.9955372,0.0009092241,0.0009122054,0.0004121521,0.001139613,0.001089676],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0005386244,0.0002249835,0.9336942,0.0001142138,0.00006698479,0.0009352951,0.002318689,0.0002418849,0.0004531876,0.0001976208,0.003738746,0.05747559],"study_design_scores_gemma":[0.00007548772,0.0003462789,0.9934796,0.0001153312,0.00004778309,0.00105096,0.001383116,0.0003138077,0.0001484959,0.00004534871,0.002973049,0.0000206559],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9873213,0.007266811,0.0004503605,0.0007013173,0.00008061315,0.0002297373,0.000596925,0.00002153549,0.003331429],"genre_scores_gemma":[0.9920797,0.003653989,0.001353445,0.000731911,0.0001627456,0.0001372868,0.001308337,0.00002785402,0.0005447679],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07204854,"threshold_uncertainty_score":0.1432583,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03122843870408421,"score_gpt":0.2915604792796188,"score_spread":0.2603320405755346,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}