{"id":"W7108742579","doi":"10.1182/blood-2025-2402","title":"Expansion, differentiation, and culture of hematopoietic stem & progenitor cells using an ancillary GMP-compliant medium","year":2025,"lang":"en","type":"article","venue":"Blood","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Terry Fox Research Institute; Stemcell Technologies","funders":"","keywords":"Progenitor cell; Haematopoiesis; Cord blood; Stem cell; Cell therapy; CD34; Induced pluripotent stem cell; Cell culture","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004016613,0.0004380136,0.0002570199,0.0003673851,0.000269294,0.0004040329,0.0004432671,0.0002583789,0.0007326171],"category_scores_gemma":[0.0002417933,0.0001171903,0.0002160372,0.0003645569,0.0002133966,0.0001790904,0.0004286642,0.0005119448,0.0005991785],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001919184,"about_ca_system_score_gemma":0.00044007,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004966088,"about_ca_topic_score_gemma":0.0009007251,"domain_scores_codex":[0.9997123,0.0000343443,0.00005321983,0.00004863318,0.0001295619,0.00002188082],"domain_scores_gemma":[0.9998173,0.0000404062,0.00004156042,0.00003077133,0.00004381035,0.00002602732],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004860147,0.00005556632,0.0002887554,0.00009145651,0.000003422426,0.0001093719,0.00003453276,0.0002653377,0.9951447,0.0002798558,0.0001731905,0.003505148],"study_design_scores_gemma":[0.00001070779,0.0001117522,0.001041694,0.00002139624,0.0000156638,0.000175205,0.00001405503,0.001381212,0.9894939,0.00006027733,0.007667121,0.000006856242],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8276958,0.003161167,0.1461311,0.0002386444,0.0002197206,0.00179888,0.004533904,0.0009869345,0.01523386],"genre_scores_gemma":[0.8149799,0.002383285,0.1667744,0.0001589929,0.00006214091,0.00187436,0.005613932,0.0001380225,0.008015008],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007326171,"threshold_uncertainty_score":0.002450883,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03631323697064287,"score_gpt":0.3097579594756162,"score_spread":0.2734447225049734,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}