{"id":"W7110497740","doi":"","title":"Evaluation of Avenanthramide-A as a skin penetration enhancer: In vitro and in vivo testing on permeation of Magnesium ascorbyl phosphate and Diclofenac sodium from topical gels","year":2025,"lang":"","type":"article","venue":"Digital Commons - LIU Promoting Scholarship and Creative Work of LIU Students, Faculty, and Staff (Long Island University)","topic":"Advancements in Transdermal Drug Delivery","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Stratum corneum; Permeation; Penetration (warfare); Transdermal; Active ingredient; Excipient; Dosage form; Magnesium stearate; Hydroxypropyl cellulose","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006232053,0.0005493299,0.0005214051,0.0003166684,0.0002494733,0.0002913076,0.0002801412,0.0004585521,0.001001014],"category_scores_gemma":[0.0003962192,0.000250333,0.0007890211,0.0003358636,0.0002388847,0.0005992174,0.0002104528,0.0007184432,0.0002279161],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001714378,"about_ca_system_score_gemma":0.0003143154,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000961147,"about_ca_topic_score_gemma":0.001445534,"domain_scores_codex":[0.9996563,0.00008823263,0.00003938999,0.00007359798,0.00008869141,0.00005371542],"domain_scores_gemma":[0.9995559,0.000122775,0.0000971999,0.00003103651,0.0001325776,0.00006037582],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003484284,0.0003837088,0.0001855747,0.000270619,0.00001829411,0.00007385665,0.00006934386,0.0001281674,0.9959194,0.00003180087,0.00005103976,0.002519813],"study_design_scores_gemma":[0.00004209442,0.007939192,0.002685242,0.00002679295,0.00008601112,0.0002228195,0.00008081431,0.0006383446,0.9864819,0.00002044916,0.001761437,0.00001486756],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9874537,0.00823274,0.002131746,0.0001630707,0.00007649422,0.0001757413,0.000308009,0.00004441147,0.001414132],"genre_scores_gemma":[0.9806187,0.008768544,0.007317978,0.00009370915,0.00003567101,0.000124784,0.0003157244,0.00002708529,0.00269791],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001001014,"threshold_uncertainty_score":0.003348708,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06103582071454523,"score_gpt":0.3753969940542635,"score_spread":0.3143611733397182,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}