{"id":"W7112042610","doi":"","title":"Differential proinflammatory responses to Aspergillus fumigatus by airway epithelial cells in vitro are protease dependant","year":2021,"lang":"en","type":"article","venue":"Research Explorer (The University of Manchester)","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"","keywords":"Proteases; Aspergillus fumigatus; Proinflammatory cytokine; Protease; Cysteine protease; Interleukin 8; Cytokine; Immune system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003549351,0.000320782,0.0003097798,0.0001466434,0.0001880085,0.0003541037,0.00009324057,0.0002970072,0.001448388],"category_scores_gemma":[0.0002356289,0.0001837611,0.0003571516,0.0001587639,0.000198156,0.0002164908,0.0002697596,0.0006340052,0.0004011141],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001701387,"about_ca_system_score_gemma":0.0001490694,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004208804,"about_ca_topic_score_gemma":0.0007991807,"domain_scores_codex":[0.9994416,0.0001884875,0.00007664225,0.00005747223,0.0001177851,0.0001179817],"domain_scores_gemma":[0.9997761,0.00009735446,0.0000259515,0.00003310446,0.00003516613,0.0000323699],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002306133,0.00005859224,0.0005597739,0.00005170461,0.000006069492,0.00006284039,0.00004341099,0.00003252412,0.9982383,0.00002165287,0.00002940014,0.000665074],"study_design_scores_gemma":[0.00005201632,0.002261672,0.03583454,0.00002314108,0.00004551939,0.0004986968,0.0002690311,0.0007453975,0.9587197,0.00007414418,0.001467396,0.000008790168],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9960595,0.001414201,0.000954947,0.0001137481,0.00004343948,0.00004781689,0.0002866295,0.00001392658,0.001065816],"genre_scores_gemma":[0.9959812,0.0009256243,0.001220781,0.0001027135,0.00003209773,0.0000717028,0.000513083,0.000004646995,0.001148261],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001448388,"threshold_uncertainty_score":0.004845381,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0416623252026783,"score_gpt":0.2854831162505749,"score_spread":0.2438207910478966,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}