{"id":"W7113905575","doi":"10.3390/jcm14248749","title":"Inborn Errors of Amino Acid Metabolism Revisited: Clinical Implications and Insights into Current Therapies","year":2025,"lang":"en","type":"article","venue":"Journal of Clinical Medicine","topic":"Metabolism and Genetic Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Children's Health Foundation","keywords":"Transplantation; Narrative review; Liver transplantation; Amino acid metabolism; Amino acid; Clinical trial; Catabolism; Disease","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004577252,0.0007996445,0.002002246,0.002866216,0.0003953524,0.002542316,0.0009909718,0.001951358,0.004152249],"category_scores_gemma":[0.009422456,0.0002547583,0.001052202,0.002869489,0.001458226,0.003892646,0.001324192,0.002632623,0.0008660631],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001433163,"about_ca_system_score_gemma":0.003935908,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001170617,"about_ca_topic_score_gemma":0.002322048,"domain_scores_codex":[0.9982602,0.00075004,0.0004091488,0.0001660109,0.0003157059,0.00009894397],"domain_scores_gemma":[0.9912048,0.006399924,0.001222342,0.0001233407,0.0008685053,0.0001810351],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000710554,0.00007114316,0.001344709,0.1164221,0.0008234604,0.001470666,0.0007366535,0.0005556107,0.001345736,0.02795035,0.04457855,0.8039904],"study_design_scores_gemma":[0.0001282288,0.000379697,0.002773448,0.1696816,0.001443109,0.00583251,0.001526776,0.0003367699,0.0008175555,0.04247208,0.7745336,0.00007465405],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002082752,0.9939721,0.0001722659,0.004504839,0.0004640484,0.000003908204,0.00002974369,0.000004729356,0.0006401431],"genre_scores_gemma":[0.004298672,0.9915587,0.0004993809,0.002273231,0.001049992,0.00001527396,0.00004825999,0.000004542369,0.0002520733],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004577252,"threshold_uncertainty_score":0.02420712,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04006102696306956,"score_gpt":0.4313066852343458,"score_spread":0.3912456582712763,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}