{"id":"W7114902100","doi":"10.53366/jimki.vi.953","title":"Associations Between Genetic Variants and Adverse Effects of Gefitinib in Non-small Cell Lung Cancer: A Systematic Review","year":2025,"lang":"","type":"article","venue":"JIMKI Jurnal Ilmiah Mahasiswa Kedokteran Indonesia","topic":"Lung Cancer Treatments and Mutations","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Gefitinib; Adverse effect; Lung cancer; Pharmacogenomics; Erlotinib; Pharmacogenetics; Genetic testing; CYP2D6; Meta-analysis","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.005264282,0.001030333,0.007096314,0.006084104,0.0004614145,0.001670563,0.001403524,0.001395488,0.003620548],"category_scores_gemma":[0.02355685,0.0005957283,0.007324429,0.008019877,0.0006358981,0.001327524,0.0008551967,0.0006877181,0.0002165589],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002049501,"about_ca_system_score_gemma":0.006253488,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006965784,"about_ca_topic_score_gemma":0.01924043,"domain_scores_codex":[0.9950185,0.001439935,0.002158262,0.00046692,0.0007571473,0.0001592502],"domain_scores_gemma":[0.9779437,0.0156757,0.004393183,0.0002916074,0.001507701,0.0001880851],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"systematic_review","study_design_gemma":"systematic_review","study_design_scores_codex":[0.0002266173,0.000009664637,0.00240472,0.961977,0.01919269,0.0001270187,0.00009972468,0.0001051764,0.0001425298,0.000103713,0.001002068,0.01460912],"study_design_scores_gemma":[0.0005114502,0.000302345,0.01947912,0.7202443,0.24311,0.0007218619,0.000230486,0.0001711542,0.0002658039,0.0003829569,0.0145213,0.00005935719],"study_design_candidate":"systematic_review","study_design_consensus":"systematic_review","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.003180665,0.994662,0.0001485177,0.0002736164,0.00008166624,0.0002696314,0.001089644,0.000009766571,0.0002844827],"genre_scores_gemma":[0.05331986,0.9432483,0.0007221021,0.0007990891,0.0001302184,0.0007561696,0.000814356,0.000009303373,0.0002006267],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.007096314,"threshold_uncertainty_score":0.0278405,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007255484987686441,"score_gpt":0.297768045910995,"score_spread":0.2905125609233085,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}