{"id":"W7114927637","doi":"10.3390/nano15241869","title":"Curcumin-Loaded Nanoscale Metal–Organic Frameworks for Therapeutic Applications in Cancer","year":2025,"lang":"en","type":"article","venue":"Nanomaterials","topic":"Curcumin's Biomedical Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"","keywords":"Nanocarriers; Photothermal therapy; Biocompatible material; Curcumin; Cancer; Nanomedicine; Cancer treatment; Drug delivery","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000169383,0.0001594805,0.0002300897,0.00007435359,0.00008948347,0.00003284248,0.0003046612,0.0004282501,0.0001471253],"category_scores_gemma":[0.00004973742,0.000147002,0.00007925918,0.0002900336,0.00009812202,0.00000343021,0.00009065183,0.00006675543,0.00001159214],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003748213,"about_ca_system_score_gemma":0.0001443444,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002636094,"about_ca_topic_score_gemma":0.00002906662,"domain_scores_codex":[0.9988794,0.0000392578,0.0003382533,0.0004091878,0.00007476691,0.0002591661],"domain_scores_gemma":[0.9993132,0.00005017262,0.00008577028,0.0004298765,0.00006870893,0.00005224457],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000028559,0.0001188782,0.0003934259,0.00004295724,0.00004953019,7.814473e-8,0.00002121287,0.000001133936,0.9941859,0.001526938,0.001161069,0.002470278],"study_design_scores_gemma":[0.0003949118,0.00002767004,0.0009426094,0.00001554932,0.00003744421,5.696598e-7,0.00002445494,0.000005717429,0.7763134,0.00224621,0.2198671,0.0001244093],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8860484,0.003721688,0.1037886,0.002644769,0.000584586,0.002418968,0.0003215439,0.00005891506,0.00041252],"genre_scores_gemma":[0.9924949,0.0001235787,0.0007708922,0.0008209589,0.0002257221,0.003779449,0.0003252283,0.00002475641,0.001434523],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.218706,"threshold_uncertainty_score":0.5994568,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01194838136339045,"score_gpt":0.3138671429786258,"score_spread":0.3019187616152354,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}