{"id":"W7115028461","doi":"","title":"DDX5 prevents RNA accumulation at DNA double strand breaks to facilitate end resection and homologous recombination repair","year":2025,"lang":"en","type":"dissertation","venue":"eScholarship@McGill (McGill)","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Homologous recombination; Double strand; DNA; RNA; Non-homologous end joining; Recombination; DNA damage","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001652251,0.000330497,0.0003590764,0.0002334065,0.0001917345,0.0003428307,0.0002391219,0.0003514604,0.002107466],"category_scores_gemma":[0.00009883923,0.0002066084,0.0003145414,0.0001184747,0.0002143894,0.0002188363,0.0002808794,0.0006149005,0.0003275637],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002783636,"about_ca_system_score_gemma":0.0001784611,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004676308,"about_ca_topic_score_gemma":0.0007856151,"domain_scores_codex":[0.9997336,0.00002842081,0.00003552808,0.00007772504,0.00007232261,0.00005236348],"domain_scores_gemma":[0.9998931,0.00001218049,0.00003562478,0.00001245647,0.00001017302,0.00003653992],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008056778,0.00003917934,0.0001864179,0.00009304761,0.000006011918,0.00002878371,0.00001197719,0.0000495769,0.9981201,0.00008507008,0.00007254106,0.001226673],"study_design_scores_gemma":[0.000009728759,0.0002140633,0.00320986,0.000008012204,0.00001064303,0.0001067368,0.00001999081,0.0004714334,0.9929773,0.000023002,0.002946313,0.000002843553],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9831714,0.006082441,0.006926996,0.0001563585,0.0001371815,0.00007201676,0.001032569,0.0002840611,0.002136918],"genre_scores_gemma":[0.9895661,0.001124184,0.003107677,0.00009021604,0.00001184233,0.00004639249,0.001008051,0.0000290969,0.005016617],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002107466,"threshold_uncertainty_score":0.007050216,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03001578097647951,"score_gpt":0.2741371029843108,"score_spread":0.2441213220078313,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}