{"id":"W7115067358","doi":"10.1136/jnnp-2025-abn.21","title":"21 Long-term safety and efficacy of nipocalimab in generalized myasthenia gravis: vivacity-MG3 open-label extension phase results","year":2025,"lang":"","type":"article","venue":"","topic":"Myasthenia Gravis and Thymoma","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; University Health Network","funders":"","keywords":"Placebo; Myasthenia gravis; Randomized controlled trial; Phase (matter); Clinical trial","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001879262,0.0008507732,0.001501173,0.0001972217,0.00031592,0.0006272508,0.000616084,0.001041779,0.003838903],"category_scores_gemma":[0.0009603487,0.0002608449,0.001067239,0.0001945776,0.0005986092,0.0005313245,0.0003000157,0.001814141,0.0006705719],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005265622,"about_ca_system_score_gemma":0.001061535,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008403639,"about_ca_topic_score_gemma":0.001435156,"domain_scores_codex":[0.999527,0.0002388839,0.0000286502,0.00005036579,0.00005702023,0.00009810293],"domain_scores_gemma":[0.9992772,0.000143472,0.0001700197,0.0000935711,0.00005676067,0.0002590731],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.766572,0.02986978,0.004620364,0.001150464,0.0008414621,0.0003037123,0.0001954264,0.001082654,0.06539895,0.0002423947,0.005992643,0.1237301],"study_design_scores_gemma":[0.4110414,0.550433,0.02149306,0.00008314484,0.0005775107,0.0003642625,0.00005425332,0.0008048287,0.009820026,0.000288685,0.004995074,0.0000446114],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9890147,0.003288385,0.000537534,0.0003828856,0.0001024868,0.001935973,0.002229218,0.0001030716,0.002405718],"genre_scores_gemma":[0.9896575,0.001108968,0.001051798,0.0009190541,0.0001584679,0.001299484,0.003446844,0.00002411983,0.002333846],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003838903,"threshold_uncertainty_score":0.01284242,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04031033598930187,"score_gpt":0.3645523754725014,"score_spread":0.3242420394831995,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}