{"id":"W7116094266","doi":"10.1016/j.ymeth.2025.12.006","title":"Development of a novel microsampling device to standardize the analysis of intranasal inflammatory biomarkers","year":2025,"lang":"en","type":"article","venue":"Methods","topic":"Sinusitis and nasal conditions","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"","keywords":"Biomarker; Nasal administration; Biomarker discovery; Analyte; Reliability (semiconductor); Coefficient of variation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001476105,0.000585668,0.0004282107,0.0006086871,0.0001958841,0.0006045319,0.0006943069,0.0008479523,0.0006691489],"category_scores_gemma":[0.001784676,0.0003407386,0.0004571821,0.0002495359,0.0004109459,0.0006305153,0.0004808022,0.0006283802,0.0003946255],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003432977,"about_ca_system_score_gemma":0.0005238463,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004455398,"about_ca_topic_score_gemma":0.000939187,"domain_scores_codex":[0.998925,0.0001349901,0.0000876453,0.0002621471,0.0005436467,0.00004658039],"domain_scores_gemma":[0.9991975,0.0002610982,0.0001888184,0.0001024392,0.0002133244,0.0000367991],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006856134,0.00004954827,0.001090147,0.0001655321,0.00001556661,0.00006925132,0.00006330036,0.0002621151,0.9796358,0.0003369552,0.0002455018,0.0179977],"study_design_scores_gemma":[0.00002196037,0.0006140483,0.006292486,0.00003294146,0.00005250053,0.000614524,0.00006397322,0.007882334,0.9740326,0.0001950137,0.01015183,0.00004593085],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.3954074,0.005263755,0.5900599,0.000735444,0.0007921845,0.001598689,0.001240062,0.001744939,0.003157689],"genre_scores_gemma":[0.4670763,0.001982677,0.5252787,0.0005507898,0.0001551573,0.001269434,0.0006328781,0.00009720927,0.002956798],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.001476105,"threshold_uncertainty_score":0.00780648,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0564041055721583,"score_gpt":0.4415005590963867,"score_spread":0.3850964535242284,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}