{"id":"W7116424082","doi":"10.1155/dth/9999376","title":"Efficacy and Safety of Ablative Fractional CO <sub>2</sub> Laser Therapy for Localized Scleroderma: A Comprehensive Bench‐to‐Bedside Approach","year":2025,"lang":"en","type":"article","venue":"Dermatologic Therapy","topic":"Systemic Sclerosis and Related Diseases","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"SKiN Health","funders":"Natural Science Foundation of Hunan Province; National Natural Science Foundation of China","keywords":"Ablative case; Adverse effect; Lesion; Clinical trial; Fibrosis; Therapeutic effect; Scleroderma (fungus); Animal study","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001488749,0.0002894728,0.000808437,0.0002145203,0.0001800714,0.0000194582,0.00011361,0.0002528643,0.00002314053],"category_scores_gemma":[0.00007344812,0.0002034737,0.000205384,0.0003430904,0.0002189134,0.00005904613,0.00002517923,0.0001742741,0.000005982679],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004305574,"about_ca_system_score_gemma":0.0001476406,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009004407,"about_ca_topic_score_gemma":4.57087e-7,"domain_scores_codex":[0.9982771,0.0001750313,0.0005681772,0.0004479446,0.0002393152,0.0002924597],"domain_scores_gemma":[0.9982544,0.000790892,0.0002028054,0.0003037797,0.0002941943,0.0001538961],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.06908933,0.007332113,0.08942882,0.001181718,0.009095938,0.00005307702,0.005559941,0.002172662,0.5771753,0.004987325,0.0923275,0.1415963],"study_design_scores_gemma":[0.06905514,0.001098436,0.5027683,0.001534333,0.0003093354,0.000261495,0.002672829,0.002264356,0.389464,0.0009355466,0.02887501,0.0007612305],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9777768,0.01154243,0.005322136,0.001687135,0.0001420964,0.002726994,0.00006491889,0.00009181742,0.000645665],"genre_scores_gemma":[0.9854162,0.007375786,0.0006943587,0.006025365,0.00004443648,0.0002568293,0.0001311963,0.00002348815,0.00003238352],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4133395,"threshold_uncertainty_score":0.8297418,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03269893167993725,"score_gpt":0.300309493540117,"score_spread":0.2676105618601797,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}