{"id":"W7116451421","doi":"10.5061/dryad.g79cnp64d","title":"N1-methylpseudouridine enhances immunogenicity of RNA/lipidnanoparticle vaccines targeting SARS-CoV-2 spike and the model antigen ovalbumin","year":2025,"lang":"en","type":"dataset","venue":"Open MIND","topic":"","field":"","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"National Research Council Canada","funders":"","keywords":"Immunogenicity; RNA; Antigen; Ovalbumin; Uridine; Immune system; Epitope","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002226578,0.0003464334,0.0002191675,0.0001465688,0.00006562077,0.0001889051,0.0001403793,0.0002752038,0.0005703048],"category_scores_gemma":[0.0002060563,0.0001166222,0.0001841709,0.00009713023,0.0001493583,0.0002227496,0.0001132759,0.0003972428,0.0001224028],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001649257,"about_ca_system_score_gemma":0.0001690472,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005254741,"about_ca_topic_score_gemma":0.0009005809,"domain_scores_codex":[0.9998317,0.00003748739,0.00001538479,0.00002624209,0.00004922495,0.00003999015],"domain_scores_gemma":[0.9998525,0.00004572178,0.00004843328,0.000008672063,0.00001993592,0.00002479679],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001841785,0.00005248632,0.00006499517,0.00002271461,0.000002677128,0.00001221111,0.000009368739,0.0001260468,0.9987732,0.00001199203,0.000006485892,0.0007336828],"study_design_scores_gemma":[0.00001018422,0.002054631,0.001041311,0.000002186097,0.00001045534,0.00003195257,0.000006500076,0.0007681894,0.9958358,0.00000680867,0.0002292777,0.000002618071],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"dataset","genre_scores_codex":[0.9988648,0.0002748181,0.0004436074,0.00001620985,0.000009827752,0.00001408998,0.00003136046,0.0000144522,0.000330742],"genre_scores_gemma":[0.9978778,0.0002853287,0.001032486,0.00002051451,0.000007854149,0.00001351931,0.00007560183,0.000008326467,0.0006785464],"genre_candidate":"dataset","genre_consensus":null,"teacher_disagreement_score":0.0005703048,"threshold_uncertainty_score":0.001907825,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03651208172992982,"score_gpt":0.3383321159718299,"score_spread":0.3018200342419001,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}