{"id":"W7116631015","doi":"10.1080/13506129.2025.2605332","title":"Untwisted amyloid fibrils from a transgenic mouse model of AL amyloidosis","year":2025,"lang":"en","type":"article","venue":"Amyloid","topic":"Amyloidosis: Diagnosis, Treatment, Outcomes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Hospital","funders":"Fondation pour la Recherche Médicale; Fondazione Cariplo; Agence Nationale de la Recherche; Fondazione AIRC per la ricerca sul cancro ETS","keywords":"AL amyloidosis; Genetically modified mouse; Amyloidosis; Amyloid fibril; Amyloid (mycology); Transgene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001719423,0.001096782,0.0008433841,0.0006905138,0.0003960238,0.001379399,0.001360064,0.002431062,0.002261996],"category_scores_gemma":[0.002727185,0.0003193957,0.0005725179,0.0002213495,0.0006968447,0.0009078658,0.0003958394,0.006240904,0.001244927],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003720325,"about_ca_system_score_gemma":0.0004299634,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003129352,"about_ca_topic_score_gemma":0.0006283,"domain_scores_codex":[0.9992353,0.0001097527,0.0001051539,0.0001077541,0.000386608,0.00005537252],"domain_scores_gemma":[0.9975421,0.001116268,0.000225646,0.00005983422,0.0007075585,0.0003485458],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001321133,0.0002699576,0.0008728012,0.0008506718,0.00009842575,0.002993361,0.0001023245,0.0001862618,0.02278377,0.003199652,0.8989965,0.0683252],"study_design_scores_gemma":[0.0003471634,0.0006569333,0.002818942,0.0004222771,0.0003554995,0.005471813,0.0001206574,0.001462384,0.01791384,0.002954479,0.9673961,0.00007987203],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"editorial","genre_gemma":"empirical","genre_scores_codex":[0.01271937,0.05743989,0.005359209,0.1635003,0.754231,0.0001302847,0.0007241741,0.0004306466,0.005465105],"genre_scores_gemma":[0.03631527,0.06771335,0.003809531,0.08849759,0.7537214,0.0001881244,0.0005587552,0.0001982504,0.04899777],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.002431062,"threshold_uncertainty_score":0.009093344,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01341149321378635,"score_gpt":0.2661433084622371,"score_spread":0.2527318152484507,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}