{"id":"W7116677603","doi":"10.58931/cibdt.2025.3348","title":"Is IL-23 the Winner? Lessons from Inflammatory Bowel Disease (IBD) and Psoriasis (PsO)","year":2025,"lang":"","type":"article","venue":"Canadian IBD Today","topic":"Psoriasis: Treatment and Pathogenesis","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Inflammatory bowel disease; Psoriasis; Ulcerative colitis; Disease; Crohn's disease; Inflammatory Bowel Diseases; Clinical trial; Pathogenesis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.008037262,0.001024748,0.002491106,0.001366916,0.001412821,0.004206921,0.001663119,0.005919374,0.00854467],"category_scores_gemma":[0.01287429,0.0004011463,0.001197374,0.00118553,0.005173191,0.008266276,0.002965,0.01805713,0.003328516],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003340592,"about_ca_system_score_gemma":0.005543988,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.007864021,"about_ca_topic_score_gemma":0.01809113,"domain_scores_codex":[0.9977835,0.0007161835,0.0002013789,0.0003009062,0.0006823909,0.0003157014],"domain_scores_gemma":[0.9865757,0.006665446,0.0004486851,0.0004932318,0.003121012,0.002695977],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0006667097,0.0001465629,0.001167562,0.0035604,0.0001824504,0.0008459623,0.0007304024,0.0004016793,0.0008683687,0.04116724,0.5093357,0.440927],"study_design_scores_gemma":[0.0001322241,0.0002152489,0.001265404,0.004023686,0.00009924817,0.001002274,0.001823363,0.0001800217,0.0003795135,0.08381358,0.9069821,0.00008326776],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"review","genre_gemma":"commentary","genre_scores_codex":[0.0006688655,0.7090575,0.0008108403,0.265672,0.01999193,0.0000100062,0.00009710815,0.00005235376,0.003639361],"genre_scores_gemma":[0.01682024,0.8101937,0.001661164,0.1187144,0.04688348,0.00003862197,0.00009523425,0.00005840532,0.005534838],"genre_candidate":"commentary","genre_consensus":null,"teacher_disagreement_score":0.00854467,"threshold_uncertainty_score":0.04250556,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01321583376712472,"score_gpt":0.2325306366441286,"score_spread":0.2193148028770039,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}