{"id":"W7116744267","doi":"10.5858/arpa.2025-0261-le","title":"Incipient Intracholecystic Papillary-Tubular Neoplasms Harboring CTNNB1 Mutations and β-Catenin Aberrant Expression: CTNNB1 Mutations in Incipient ICPNs","year":2025,"lang":"en","type":"article","venue":"Archives of Pathology & Laboratory Medicine","topic":"Genetic and Kidney Cyst Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University Hospital Foundation","funders":"","keywords":"Mutation; Gene; Phenotype; Gene deletion","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002448248,0.0008087261,0.0004906686,0.001344299,0.0005038184,0.0007161351,0.0006926001,0.0009098684,0.002551792],"category_scores_gemma":[0.001166454,0.0003735285,0.000329041,0.0006945533,0.001149064,0.0005080216,0.0008180891,0.0007228391,0.0004321678],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006258133,"about_ca_system_score_gemma":0.000541343,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001462825,"about_ca_topic_score_gemma":0.001387055,"domain_scores_codex":[0.9996629,0.00001982354,0.0000417544,0.00008055621,0.0001067593,0.00008832085],"domain_scores_gemma":[0.9992653,0.0001503853,0.0002380584,0.00006998511,0.00007836473,0.0001979755],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001239789,0.0001135472,0.1202779,0.0001428209,0.00005552889,0.7130107,0.0005987922,0.0004347795,0.154422,0.001087412,0.0002905023,0.008326336],"study_design_scores_gemma":[0.00004729887,0.0001759999,0.1311771,0.0000288688,0.0001512257,0.8149771,0.0004617863,0.001898926,0.04829841,0.000746369,0.002001956,0.00003503003],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9945847,0.0002306562,0.0009321883,0.00008985451,0.00001327858,0.00002200437,0.000135664,0.00006905217,0.003922511],"genre_scores_gemma":[0.9989323,0.00007686151,0.0005406868,0.00001671269,0.00001601352,0.00000586519,0.0000609583,0.00002115093,0.0003294642],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002551792,"threshold_uncertainty_score":0.008536577,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005429522694518227,"score_gpt":0.2519379835016448,"score_spread":0.2465084608071265,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}