{"id":"W7116849294","doi":"10.51731/cjht.2025.1315","title":"Abemaciclib (Verzenio)","year":2025,"lang":"","type":"article","venue":"Canadian Journal of Health Technologies","topic":"Advanced Breast Cancer Therapies","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Fulvestrant; Breast cancer; Metastatic breast cancer; Chemotherapy; Reimbursement; Regimen; Cancer; Aromatase","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001276521,0.0004295972,0.001434827,0.002814315,0.0006207838,0.00007338253,0.0009654376,0.0005050949,0.0002145024],"category_scores_gemma":[0.001544291,0.000397878,0.000283467,0.001702258,0.00126686,0.000282018,0.00006352726,0.001839668,0.0000336739],"about_ca_system_candidate":true,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003235739,"about_ca_system_score_gemma":0.029728,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004216227,"about_ca_topic_score_gemma":0.003333305,"domain_scores_codex":[0.9957976,0.0001401649,0.001892935,0.0003541644,0.0003270289,0.001488068],"domain_scores_gemma":[0.9967495,0.0001690834,0.001293019,0.0007906882,0.0006905805,0.0003071966],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001226485,0.00003552606,0.005875684,0.000721014,0.0003539965,0.0003982749,0.0004538256,0.00002707703,0.0000595065,0.005756513,0.005193824,0.9810021],"study_design_scores_gemma":[0.002601488,0.0009914611,0.01015411,0.005910525,0.0001415269,0.0007857034,0.0139062,0.00001599409,0.001514693,0.02296452,0.9407075,0.0003062776],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.01158076,0.7765502,0.003941523,0.2014146,0.004152824,0.000598984,0.00005104012,0.0001544897,0.001555646],"genre_scores_gemma":[0.9860482,0.007050902,0.001657334,0.003879658,0.00005865959,0.000009154208,0.000001857946,0.00004160542,0.001252651],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.9806958,"threshold_uncertainty_score":0.9998473,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01801521838935656,"score_gpt":0.3289363002768032,"score_spread":0.3109210818874466,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}