{"id":"W7116849294","doi":"10.51731/cjht.2025.1315","title":"Abemaciclib (Verzenio)","year":2025,"lang":"","type":"article","venue":"Canadian Journal of Health Technologies","topic":"Advanced Breast Cancer Therapies","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Fulvestrant; Breast cancer; Metastatic breast cancer; Chemotherapy; Reimbursement; Regimen; Cancer; Aromatase","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004217023,0.0002867909,0.0004123034,0.001129595,0.0002852991,0.001135575,0.0004285539,0.0004428494,0.01897854],"category_scores_gemma":[0.00081288,0.0001019799,0.0004241042,0.000887435,0.0002587102,0.0006023668,0.0002766747,0.0007992309,0.002709371],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002142365,"about_ca_system_score_gemma":0.002618779,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0218614,"about_ca_topic_score_gemma":0.07196251,"domain_scores_codex":[0.9996842,0.00005543751,0.00003061965,0.00004826361,0.000145935,0.00003546759],"domain_scores_gemma":[0.9997371,0.00005324572,0.00006192998,0.000009741107,0.00009629488,0.00004160534],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0008315473,0.0001219332,0.0004276552,0.006663579,0.0001105294,0.0001776232,0.00004947518,0.0002327255,0.005219278,0.005375769,0.08987205,0.890918],"study_design_scores_gemma":[0.0005161411,0.0004202641,0.002077022,0.002679313,0.0002012281,0.0006964456,0.00003845647,0.0001339135,0.002632243,0.000659483,0.9899265,0.00001896224],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01534432,0.7631221,0.001389081,0.004002242,0.001115369,0.0006415584,0.00457488,0.0003372927,0.2094731],"genre_scores_gemma":[0.1896231,0.6791832,0.004651116,0.007982766,0.000657185,0.0004106375,0.007286648,0.0001143105,0.110091],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.0218614,"threshold_uncertainty_score":0.06348956,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01801521838935656,"score_gpt":0.3289363002768032,"score_spread":0.3109210818874466,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}