{"id":"W7116856229","doi":"10.3390/curroncol33010006","title":"Changes in HER2, ER, PR, and Ki-67 in HER2-Negative Breast Cancer After Neoadjuvant Chemotherapy: A Case–Control Study","year":2025,"lang":"en","type":"article","venue":"Current Oncology","topic":"Breast Cancer Treatment Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Natural Science Foundation of China","keywords":"Immunohistochemistry; Breast cancer; Progesterone receptor; Estrogen receptor; Logistic regression; Human Epidermal Growth Factor Receptor 2; Univariate analysis; Hormone receptor","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001195214,0.0003383073,0.0003954509,0.0009425881,0.0006718856,0.0005174004,0.000418663,0.0005409113,0.001190946],"category_scores_gemma":[0.002560342,0.0005187473,0.0004003179,0.0007638715,0.0005990478,0.0003898375,0.000329576,0.0003848587,0.0002667791],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005160703,"about_ca_system_score_gemma":0.0002882047,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003527506,"about_ca_topic_score_gemma":0.003480269,"domain_scores_codex":[0.9990624,0.000260438,0.0001147613,0.0002772953,0.0001783274,0.0001068746],"domain_scores_gemma":[0.9985518,0.0003913441,0.0005209084,0.0002552343,0.000139623,0.0001410833],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0004748317,0.0001983646,0.9962346,0.00001664262,0.00005862539,0.0007636424,0.0001285683,0.00002032451,0.0005867134,0.0000196657,0.00006457896,0.00143346],"study_design_scores_gemma":[0.00007235345,0.0006798151,0.9934645,0.000007136126,0.00008018326,0.004423936,0.0002235256,0.0002040882,0.0002750189,0.00002319271,0.0005366189,0.000009627329],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9993597,0.0002788993,0.00008588815,0.00001008851,0.000006685937,0.00001420428,0.00005016806,0.000002216907,0.0001921443],"genre_scores_gemma":[0.9994922,0.00009607181,0.0001000875,0.0000148888,0.00001541243,0.00001845316,0.0001446563,0.00000159625,0.0001165999],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003527506,"threshold_uncertainty_score":0.007013917,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01831636666205805,"score_gpt":0.3529972279863114,"score_spread":0.3346808613242533,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}