{"id":"W7116857920","doi":"10.1002/alz70861_107951","title":"Antiviral therapy: Valacyclovir Treatment of Alzheimer's Disease (VALAD) Clinical Trial","year":2025,"lang":"en","type":"article","venue":"Alzheimer s & Dementia","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Disease; Clinical trial; Herpes simplex virus; Etiology; Antiviral treatment; Antiviral therapy; Virus","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001530963,0.0008402942,0.001801623,0.0003184145,0.0004009018,0.001158838,0.0005162396,0.001553759,0.008005092],"category_scores_gemma":[0.001211822,0.000330075,0.0009172222,0.0003026353,0.0005876814,0.0006958237,0.0003116383,0.001655009,0.0007852056],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004284034,"about_ca_system_score_gemma":0.0008740395,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004038198,"about_ca_topic_score_gemma":0.001102442,"domain_scores_codex":[0.999511,0.0002942792,0.00002967453,0.00007569322,0.00003000675,0.00005931322],"domain_scores_gemma":[0.9995598,0.0001388676,0.00006589369,0.00003125596,0.00003365594,0.0001705808],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9631154,0.002938743,0.0009034718,0.000945361,0.000552267,0.00005697916,0.00003306972,0.0002310085,0.001767936,0.0002619742,0.001790036,0.02740383],"study_design_scores_gemma":[0.970926,0.02491338,0.00172393,0.00009223804,0.0002557624,0.00004154937,0.00001265367,0.0001820383,0.0001946894,0.0002523208,0.001399457,0.000005854923],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9464762,0.03261825,0.0006678405,0.002361209,0.001827334,0.003716353,0.00285435,0.0001431246,0.00933534],"genre_scores_gemma":[0.976105,0.007641176,0.001286091,0.002159321,0.001147971,0.004033121,0.001753009,0.00001355202,0.005860724],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008005092,"threshold_uncertainty_score":0.02677965,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08227388074841763,"score_gpt":0.4005223533557248,"score_spread":0.3182484726073072,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}